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Chemesis International Inc. (the “Company”) (CSE: CSI) (OTC: CADMF) (FRA: CWAA) The Company announces that the Department of Health of Puerto Rico (“Department of Heath”) is conducting a review of certain filings made by the Company’s subsidiaries, Natural Ventures PR LLC (“ NVPR”) a

Corporate Updates

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Chemesis International Inc.

September 28, 2020

Vancouver, BC – Chemesis International Inc. (the “Company”) (CSE: CSI) (OTC: CADMF) (FRA: CWAA)

The Company announces that the Department of Health of Puerto Rico (“Department of Heath”) is conducting

a review of certain filings made by the Company’s subsidiaries, Natural Ventures PR LLC (“ NVPR”) and GSRX

Industries Inc. (“GSRX”) with the Department of Health. This review is in addition to the ongoing administrative

review by the Department of Health previously announced by the Company (see news releases dated August

7, 2020 and January 17, 2020).

The Company’s Puerto Rico legal counsel have been in contact with the Department of Health and will have an

opportunity to discuss and a ddress this matter through an administrative process expected to commence

within the next few days. The Company, through its local legal counsel, has been informed that the Licenses

will remain intact during such process.

At present, the Company’s operations under the Licenses continue in the ordinary course.

On Behalf of The Board of Directors

Josh Rosenberg

President

Investor Relations:

[email protected]

1 (604) 398-3378

Forward-Looking Information: This news release contains "forward -looking information" within the meaning of

applicable securities laws relating to statements regarding the ability of the Company to continue to operate under

the Licenses, and the ability of the Company to engage in any administrative process with the Department of Health.

Although the Company believes that the expectations reflected in the forward -looking information are reasonable,

there can be no assurance that such expectations will prove to be correct. Readers are cautioned not to place undue

reliance on forward-looking information. Such forward-looking statements are subject to risks and uncertainties that

may cause actual results, performance and developments to differ materially from those contemplated by these

statements including, among other things, the risks that the Company will not be able to maintain or continue

licensed activities under the Licences as currently being conducted, or at all, and that the Company's products and

plans will vary significantly as a result, and that the Company will not be permitted to engage with the Department

of Health through an administrative or other process to address the concerns raised. Except as required by law, the

Company expressly disclaims any obligation and does not intend to update any forward -looking statements or

forward-looking information in this news release. Although the Company believes that the expectations reflected in

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the forward-looking information are reasonable, there can be no assurance that such expec tations will prove to be

correct and makes no reference to profitability based on sales reported. The statements in this news release are made

as of the date of this release.

The CSE has not reviewed, approved or disapproved the content of this press release