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Chemesis International Inc. (the “Company”) (CSE: CSI) (OTC: CADMF) (FRA: CWAA) The Company announces that the Department of Health of Puerto Rico (“ Department of Health ”) has not renewed licenses held by GSRX Industries Inc. (“ GSRX”) which are necessary for the operation of its c

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LEGAL*51494278.1

Chemesis International Inc.

November 4, 2020

Vancouver, BC – Chemesis International Inc. (the “Company”) (CSE: CSI) (OTC: CADMF) (FRA: CWAA)

The Company announces that the Department of Health of Puerto Rico (“ Department of Health ”) has not

renewed licenses held by GSRX Industries Inc. (“ GSRX”) which are necessary for the operation of its cannabis

dispensaries in Puerto Rico, and that, as a result, GSRX’s cannabis dispensaries are no longer operating. The

Company is uncertain at this point as to whether or when such licenses will be renewed.

At present, the operations of the Company’s subsidiary, Natural Ventures PR, LLC, are continuing in the

ordinary course.

The Company notes, further to its news release dated September 28, 2020, that the Department of Health is

engaged in a review of certa in filings made by the Company’s subsidiary, GSRX Industries Inc. (“ GSRX”) with

the Department of Health, which such review is in addition to the ongoing administrative review by the

Department of Health previously announced by the Company (see news releases dated August 7, 2020 and

January 17, 2020).

The Company notes that the multiple regulatory and administrative reviews in Puerto Rico, along with

corresponding litigation (see news releases dated December 9, 201 9, January 17, 2020 and August 7, 2020),

have severely drained the Company’s financial resources and management time, resulting in significant

operational and planning difficulties. The Company further notes that it is actively working to find an

appropriate solution, with all options being on the table.

On Behalf of The Board of Directors

Josh Rosenberg

President

Investor Relations:

[email protected]

1 (604) 398-3378

LEGAL*51494278.1

Forward-Looking Information: This news release contains "forward -looking information" within the meaning of

applicable securities laws relating to statements regarding the ability of the Company to continue to operate under

the licenses held by any of its Puerto Rico subsidiaries, or at all in Puerto Rico, to further market its VICKI solutions,

or to better enhance shareholder value through the marketing of its VICKI solutions. Although the Company believes

that the expectations reflected in the forward -looking information are reasonable, there can be no assurance that

such expectations will prove to be correct. Readers are cautioned not to place undue reliance on forward -looking

information. Such forward -looking statements are subject to risks and uncertainties that may cause actual results,

performance and developments to differ materially from those contemplated by these statements including, among

other things, the risks that the Company will not be able to maintain or continue licensed activities under the licences

held by its Puerto Rico subsidiaries, that the Company may n ot be able to further market its VICKI solutions, that

focussing greater resources and attention to the marketing of the VICKI solutions may not better enhance

shareholder value, and that the Company's products and plans will vary significantly as a resul t. Except as required

by law, the Company expressly disclaims any obligation and does not intend to update any forward -looking

statements or forward -looking information in this news release. Although the Company believes that the

expectations reflected in the forward -looking information are reasonable, there can be no assurance that such

expectations will prove to be correct and makes no reference to profitability based on sales reported. The statements

in this news release are made as of the date of this release.

The CSE has not reviewed, approved or disapproved the content of this press release