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Chemesis International Inc. Signs USD $4 Million Annual Purchase Order

Mergers & Acquisitions

Chemesis, Inc. (CSE: CSI) (OTC: CADMF) (FRA:CWAA)

Chemesis International Inc. Signs USD $4 Million Annual Purchase Order

Puerto Rico based Natural Ventures signs Definitive Purchase Order for USD $4 million annually

February 28, 2019

Vancouver, BC – Chemesis International Inc. (CSE: CSI) (OTC: CADMF) (FRA: CWAA) (the “Company” or

“Chemesis”), announces its subsidiary Natural Ventures has signed a definitive agreement for an annual

purchase order of a minimum total of USD $4,000,000.

The Company will cultivate, manufacture, package and distribute for the Puerto Rico based dispensary

network from its fully licensed, state compliant facilit y. The products are white labelled under the

dispensaries brand and delivered on a weekly basis. Initial purchase orders over $400,000 USD have been

fulfilled in February and with weekly increases in the Puerto Rican medical patient base, both companies

anticipate demand to increase heading into the Q2 2019.

“Chemesis has built a strong relationship with this retail focused team, and we will ensure we supply their

dispensaries with high -quality cannabis products ,” said CEO of Chemesis, Edgar Montero. “Natural

Ventures has continued to solidify its reputation as a high-quality cultivator, and manufacturer of cannabis

products and we see this purchase order as validation. Furthermore, the Company expects to see an

increase in monthly purchase orders, as more dispensaries are opened around the island.”

Natural Ventures beg an fulfilling purchase orders in February 2019 and is providing the vendor with

edibles, vaporizers, lotions, beverages, and flower.

Due to the competitive nature of the cannabis market in Puerto Rico, the Company will not disclose who the

vendors are at this time.

On Behalf of The Board of Directors

Edgar Montero

CEO and Director

About Chemesis International Inc.

Chemesis International Inc. is a vertically integrated global leader in the cannabis industry, currently

operating within California, Puerto Rico, and Colombia.

Chemesis is developing a strong foothold in key markets, from cultivation, to manufacturing, distribution

and retail. Chemesis has facilities in both Puerto Rico and California, allowing for cost effective production

and distribution of its products. In ad dition, Chemesis leverages exclusive brands and partnerships and

uses the highest quality extraction methods to provide consumers with quality cannabis products.

Chemesis, Inc. (CSE: CSI) (OTC: CADMF) (FRA:CWAA)

Chemesis will add shareholder value by exploring opportunities in emerging markets while con sistently

delivering quality product to its consumers from seed to sale.

Investor Relations:

[email protected]

1 (604) 398-3378

Social Media:

Chemesis.facebook

Chemesis.twitter

Chemesis.instagram

DesertZen.instagram

CaliforniaSap.instagram

Jay&SB.instagram

Forward-Looking Information: This news release contains "forward -looking information" within the meaning of

applicable securities laws relating to statements regarding the Company's business, products and future of the

Company’s business, its product offerings and plans for sales and marketing, includi ng finalizing an acquisition in

Colombia. Although the Company believes that the expectations reflected in the forward -looking information are

reasonable, there can be no assurance that such expectations will prove to be correct. Readers are cautioned not to

place undue reliance on forward -looking information. Such forward -looking statements are subject to risks and

uncertainties that may cause actual results, performance and developments to differ materially from those

contemplated by these statements depe nding on, among other things, the risks that the Company's products and

plan will vary from those stated in this news release and the Company may not be able to carry out its business plans

as expected. Except as required by law, the Company expressly disclaims any obligation and does not intend to update

any forward-looking statements or forward-looking information in this news release. Although the Company believes

that the expectations reflected in the forward -looking information are reasonable, there ca n be no assurance that

such expectations will prove to be correct and makes no reference to profitability based on sales reported. The

statements in this news release are made as of the date of this release.

The CSE has not reviewed, approved or disapproved the content of this press release