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ORE.TO ·

Orezone Intersects 23.00 M of 2.84 G/T GOLD at P17S Extension at Its Bomboré GOLD MINE

Drill Results

OREZONE GOLD CORPORATION

450-505 Burrard Street

Vancouver, BC, V7X 1M3

T: 778-945-8977

[email protected]

OREZONE INTERSECTS 23.00 M OF 2.84 G/T GOLD AT P17S EXTENSION AT

ITS BOMBORÉ GOLD MINE

September 13, 2022 – Vancouver, BC - Orezone Gold Corporation (TSX: ORE, OTCQX: ORZCF) (the

“Company” or “Orezone”) is pleased to provide the final drill results from the Phase III program from

P17S-NE along the P17 mineralized trend at its Bomboré Gold Mine, located in Burkina Faso.

The focus of the Phase III drilling at P17 S was to better define the continuity of the repeat, folded

high-grade granodiorite mineralized zones.

The drill results continue to be very positive confirming the following:

• Down-plunge continuity of the mineralized zones at P17S has n ow been extended over an

additional 100 m beyond the last set of drill results, with the system still open.

• Drilling continues to intercept significant new mineralization outside of the current resource

boundaries.

• The mineralized zones remain open towards surface and at depth over a strike exceeding 300 m.

P17S Drilling Highlights:

• 23.00 m of 2.84 g/t Au from 257.00 m including 11.00 m of 5.26 g/t Au from 269.00 m in hole

BBD1125

• 12.00 m of 2.13 g/t Au from 245.00 m including 1.00 m of 19.37 g/t Au from 245.00 m in hole

BBD1124

• 3.60 m of 5.58 g/t Au from 157.00 m in hole BBD1134

• 3.80 m of 4.55 g/t Au from 312.20 m in hole BBD1141

• 8.00 m of 3.40 g/t Au from 86.00 m including 1.00 m of 17.99 g/t Au from 88.00 m in hole

BBD1133

• 11.00 m of 1.78 g/t Au from 186.00 m including 2.00 m of 7.54 g/t Au from 192.00 m in hole

BBD1143

• 3.00 m of 4.15 g/t Au from 130.00 m including 1.00 m of 10.13 g/t Au from 13 1.00 m in hole

BBD1133

Dr. Pascal Marquis, SVP of Exploration, stated, “These final drilling results at P17S confirm that this deposit

continues to grow and is still open for further exploration. We have expanded the known zones

significantly both along strike and down dip and intersected several new zones outside of the current

resource pit shell. Based on the results of this program, we expect returning to P17S to drill later in 2022.

Drilling is now well underway at the Siga deposits, which will then be followed by drilling to the North at

the Maga deposits. Results from these programs will be released throughout the remainder of 2022.”

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Table 1: P17 Trend Highlight Drill Results

Hole

#

From

(m)

To

(m)

Length

(m)*

Grade

(g/t gold)

BBD1124 144.00 162.00 18.00 0.67

and 245.00 257.00 12.00 2.13

incl. 245.00 246.00 1.00 19.37

BBD1125 257.00 280.00 23.00 2.84

incl. 269.00 280.00 11.00 5.26

BBD1126 259.00 272.00 13.00 1.45

and 278.00 288.25 10.25 1.26

BBD1133 86.00 94.00 8.00 3.40

incl. 88.00 89.00 1.00 17.99

and 101.00 112.00 11.00 0.96

incl. 110.00 111.00 1.00 4.35

and 130.00 133.00 3.00 4.15

incl. 131.00 132.00 1.00 10.13

and 167.00 176.00 9.00 1.53

incl. 174.00 175.00 1.00 6.17

BBD1134 157.00 160.60 3.60 5.58

incl. 158.00 160.60 2.60 7.34

BBD1135 188.00 194.00 6.00 1.89

incl. 191.00 194.00 3.00 2.91

BBD1141 312.20 316.00 3.80 4.55

BBD1143 186.00 197.00 11.00 1.78

incl. 192.00 194.00 2.00 7.54

* True widths for P17S drilling are approximately 90% of drilled lengths.

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Figure 1: P17 Trend Long Section Looking West

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Figure 2: Cross Section 43350 Looking North

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Figure 3: Cross Section 43400 Looking North

About Orezone Gold Corporation

Orezone Gold Corporation (TSX: ORE OTCQX: ORZCF) is a Canadian gold mining company operating the

open pit Bomboré Mine in Burkina Faso.

The technical report for the 2019 Feasibility Study on the Bomboré Project entitled NI 43-101 Technical

Report (Amended) Feasibility Study of the Bomboré Gold Project is available on SEDAR under the

Company’s profile at www.Sedar.com.

Orezone is focusing on mining and processing the Phase I near surface free-dig oxides at a planned annual

throughput of 5.2 million tonnes. T he Company believes that Bomboré has a significant underlying

sulphide resource to support a substantially larger Phase II expansion. A 77,000 m infill and expansion drill

program is ongoing and once completed, the Company plans to issue an updated mineral resource and

reserve statement and feasibility study, as part of this Phase II expansion. It is expected that the studies

will be completed in H1-2023 to be followed by a production decision.

Orezone is led by an experienced team focused on social responsibility and sustainability with a proven

track record in project construction and operations, financings, capital markets and M&A.

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Patrick Downey

President and Chief Executive Officer

Vanessa Pickering

Manager, Investor Relations

Tel: 1 778 945 8977 / Toll Free: 1 888 673 0663

[email protected] / www.orezone.com

Qualified Person

Dr. Pascal Marquis, Geo., Senior VP Exploration is the Qualified Pers on who has approved the scientific

and technical information in this news release.

QA/QC

The mineralized intervals are based on a lower cut-off grade of 0.45 g/t, a minimal width of 1.5 m and up

to a maximum of 3.0 m of dilution being included. The true width of the mineralization is approximately

90% of the drill length at P17S. The half-core drilling samples were cut using a diamond saw by Orezone

employees. The samples were prepared by SGS Burkina Faso s.a.r.l. (“SGS”) at their Ouagadougou facility

and then split by Orezone to 1 kg using Rotary Sample Dividers (“RSDs”). A 1-kg aliquot was analyzed for

leachable gold at BIGS Global Burkina s.a.r.l . (“BIGS Global”) in Ouagadougou, by bottle-roll cyanidation

using a LeachWellTM catalyst. The leach residues from all samples with a leach grade greater than or equal

to 0.4 g/t were prepared by BIGS Global and then split by Orezone to 50 g using RSDs. A 50-g aliquot was

analyzed by fire assay at BIGS Global.

Orezone employs a rigorous Quality Control Program including a minimum of 10% standards, blanks and

duplicates. The composite width and grade include the final leach residue assay results for most of the

drill intercepts reported, with the details available in the tables posted on our web site.

For further information please contact Orezone at +1 (778) 945-8977 or visit the Company’s website at

www.orezone.com.

The Toronto Stock Exchange neither approves nor disapproves t he information contained in this news

release.

Cautionary Note Regarding Forward-Looking Statements

This press release contains certain information that may constitute “forward -looking information” within the

meaning of applicable Canadian Securities laws and “forward-looking statements” within the meaning of applicable

U.S. securities laws (together, “forward -looking statements”). Forward -looking statements are frequently

characterized by words such as "plan", "expect", "project", "intend", "believe", "anticipate", "estimate", "potential",

"possible" and other similar words, or statements that certain events or conditions "may", "will", "could", or "should"

occur. Forward-looking statements in this press release include, but are not limited t o, statements with respect to

the potential at the P17S.

All such forward-looking statements are based on certain assumptions and analyses made by management in light

of their experience and perception of historical trends, current conditions and expected future developments, as well

as other factors management and the qualified persons believe are appropriate in the circumstances.

All forward-looking statements are subject to a variety of risks and uncertainties and other factors that could cause

actual events or results to differ materially from those projected in the forward-looking statements including, but not

limited to, delays caused by the COVID-19 pandemic, terrorist or other violent attacks, the failure of parties to contracts to

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honour contractual commitments, unexpected changes in laws, rules or regulations, or their enforcement by

applicable authorities; the failur e of parties to contracts to perform as agreed; social or labour unrest; changes in

commodity prices; unexpected failure or inadequacy of infrastructure, the possibility of project cost overruns or

unanticipated costs and expenses, accidents and equipment breakdowns, political risk, unanticipated changes in key

management personnel and general economic, market or business conditions, the failure of exploration programs,

including drilling programs, to deliver anticipated results and the failure of ongoing and uncertainties relating to the

availability and costs of financing needed in the future, and other factors described in the Company's most recent

annual information form and management discussion and analysis filed on SEDAR on www.sedar.com. Readers are

cautioned not to place undue reliance on forward-looking statements.

Although the forward -looking statements contained in this press release are based upon what management of the

Company believes are reasonable assumptions, the Company cannot assure investors that actual results will be

consistent with these forward-looking statements. These forward-looking statements are made as of the date of this

press release and are expressly qualified in their entirety by this cautionary statement. Subject to applicable securities

laws, the Company does not assume any obligation to update or revise the forward -looking statements contained

herein to reflect events or circumstances occurring after the date of this press release.