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Osisko Development Intersects 26.5 G/T Au over 1.5 Meters and 0.92 G/T Au over 37.5 Meters at California Target – San Antonio Project

Drill Results

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OSISKO DEVELOPMENT INTERSECTS 26.5 G/T AU OVER

1.5 METERS AND 0.92 G/T AU OVER 37.5 METERS AT

CALIFORNIA TARGET – SAN ANTONIO PROJECT

MONTREAL, February 18, 2022 – Osisko Development Corp. (“Osisko Development” or the “Company”)

(TSX.V-ODV) is pleased to announce drilling results from the 2021 exploration and category conversion

drill program campaign at its San Antonio Project in Sonora State, Mexico.

Summary

• A total of 177 holes and 27,900 meters were drilled in 2021. The objective of the drill program was

to conduct exploration and resource drilling at a spacing of 25 meters and historic drilling validation

for the three main target areas (Figure 1).

• This news releases encompasses all 5,563 meters from 27 holes at the California Target: CA-DD-

21-020 to CA-DD-21-165 inclusive (Figure 2).

• The California gold mineralization is part of what is known as the El Realito Trend, located

approximately 1 km to the southwest of Sapuchi and 4 km in length. The gold mineralization is

typically pyrite with minor chalcopyrite and associated with hydrothermal brec cia and quartzite ,

andesite and dacite intrusions.

• CA-DD-21-091 intersected 3.93 g/t Au over 13.50 meters including 26.50 g/t Au over 1.50 meters

and is located 45 meters along strike within a sulphide zone from hole CA-DD-21-085 that assayed

0.92 g/t Au over 37.50 meters.

• Detailed drilling results are presented in Table 1, drill hole locations are presented in Table 2, and

drill hole cross sections are presented in Figure 3.

Assay Highlights

• 0.63 g/t Au and 0.90 g/t Ag over 39.95 meters in hole CA-DD-21-026

• 1.50 g/t Au and 13.96 g/t Ag over 11.90 meters in hole CA-DD-21-037

• 1.73 g/t Au and 13.67 g/t Ag over 16.25 meters in hole CA-DD-21-051 including

• 12.85 g/t Au and 13.10 g/t Ag over 1.05 meters

• 1.62 g/t Au and 2.25 g/t Ag over 13.60 meters in hole CA-DD-21-064

• 1.28 g/t Au and 1.17 g/t Ag over 16.30 meters in hole CA-DD-21-070 including

• 8.21 g/t Au and 1.38 g/t Ag over 1.50 meters

• 0.92 g/t Au and 2.15 g/t Ag over 37.50 meters in hole CA-DD-21-085

• 0.87 g/t Au and 3.44 g/t Ag over 17.20 meters in hole CA-DD-21-085

• 1.56 g/t Au and 0.94 g/t Ag over 9.90 meters in hole CA-DD-21-091

• 3.93 g/t Au and 3.38 g/t Ag over 13.50 meters in hole CA-DD-21-091 including

• 26.50 g/t Au and 4.80 g/t Ag over 1.50 meters

• 0.73 g/t Au and 3.09 g/t Ag over 18.00 meters in hole CA-DD-21-100

• 2.41 g/t Au and 3.00 g/t Ag over 9.00 meters in hole CA-DD-21-100

• 0.76 g/t Au and 0.94 g/t Ag over 19.9 meters in hole CA-DD-21-113

• 2.82 g/t Au and 11.39 g/t Ag over 9.55 meters in hole CA-DD-21-116

• 21.00 g/t Au and 4.50 g/t Ag over 1.50 meters in hole CA-DD-21-0165

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Sean Roosen, CEO of Osisko Development commented, “ The California target is one of the three main

zones at the San Antonio Project. These recent drill results at California show significant anomalous results

in the oxide, transition and sulphide horizons and indicate continuity near surface and along strike and,

open to the west along trend. These results increase our confidence in the upcoming San Antonio mineral

resource estimate, which will be available in the near future. At least a dozen other target areas remain to

be drill tested.”

The S an Antonio Project gold mineralization is characterized by hydrothermal breccia that forms an

approximately 3,000 m long east -northeast trending mineralization corridor with the Luz del Cobre copper

deposit at the east. The gold mineralization is associated with intense sericite and chlorite alteration and is

intrusion related with host sedimentary rocks. The breccia has been defined to a vertical depth of

500 meters and at an average depth of 25 0 meters. The upper 250 meters of the breccia is most altered

and prospective. Drilling has occurred within the three major zones at Sapuchi, Golfo de Oro and California,

over a combined strike length of 900 meters of the 3000 - meter trend.

True widths are estimated to be 80% to 100% of reported core length intervals. Intervals not recovered by

drilling were assigned zero grade. Top cuts have not been applied to high grade assays. Complete assay

highlights are presented in Table 1, drill hole locations are listed in Table 2.

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Figure 1: San Antonio Mineral Zones overview map

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Figure 2: California Plan Map

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Figure 3: California Section select drilling highlights

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Qualified Persons

Per National Instrument 43-101 Standards of Disclosure for Mineral Projects, Maggie Layman, P.Geo. Vice

President Exploration of Osisko Development Corp. , is a Qualified Person and has prepared, validated,

and approved the technical and scientific content of this news release.

Quality Assurance – Quality Control

Once received from the drill and processed, all drill core samples are sawn in half, labelled and bagged.

The remaining drill core is subsequently stored on site at a secured facility at the project site. Numbered

security tags are applied to lab shipments for chain of custody requirements. Quality control (QC) samples

are inserted at regular intervals in the sample stream, including blanks and reference materials with all

sample shipments to monitor laboratory performance.

Drill core samples are submi tted to ALS Geochemistry and Bureau Veritas (BV) preparation laboratory in

Hermosillo and then sent to their analytical facilit ies in Vancouver, British Columbia for analysis . The

facilities are accredited to the ISO/IEC 17025 standard for gold assays and all analytical methods include

quality control materials at set frequencies with established data acceptance criteria. The entire sample is

crushed, and 20 0 grams is pulverized. Analytical packa ges for ALS and BV are AA24 and FA450

respectively. Multi Element geochemistry is also analyzed with ME MS61 at ALS and MA 200 at BV.

About Osisko Development Corp.

Osisko Development Corp. is uniquely positioned as a premier gold development company in North

America to advance the Cariboo Gold Project and other Canadian and Mexican properties, with the

objective of becoming the next mid- tier gold producer. The Cariboo Gold Project, located in central British

Columbia, is Osisko Development's flagship asset with measured and indicated resources of 21.44 Mt at

4.6 Au g/t for a total of 3.2 million ounces of gold and inferred resource of 21.69 Mt at 3.9 Au g/t for a total

of 2.7 million ounces of gold (see NI 43- 101 Technical Report and mineral resource estimate effective

October 5th, 2020) . The considerable exploration potential at depth and along strike distinguishes the

Cariboo Gold Project relative to other development assets as does the historically low, all-in discovery costs

of US $19 per ounce. The Cariboo Gold Project is advancing through permitting as a 4,750 tonnes per day

underground operation with a feasibility study on track for completion in the first half of 2022. Osisko

Development's project pipeline is complemented by potential near -term production targeted from the San

Antonio gold project, located in Sonora Mexico and early exploration stage properties including the Coulon

Project and James Bay Properties located in Québec as well as the Guerrero Properties located in Mexico.

Osisko Devel opment began trading on the TSX Venture Exchange under the symbol “ ODV” on

December 2, 2020 and the Company’s 14,789,373 outstanding share purchase warrants were listed on the

TSX Venture Exchange under the symbol “ODV.WT” on October 25, 2021.

For further information, please contact Osisko Development Corp.:

Jean Francois Lemonde

VP Investor Relations

[email protected]

Tel: 514-299-4926

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Forward-looking Statements

Certain statements contained in this press release may be deemed “forward‐looking statements” within the

meaning of applicable Canadian and U.S. securities laws. These forward ‐looking statements, by their

nature, require Osisko Development to make certain assumptions and necessarily involve known and

unknown risks and uncertainties that could cause actual results to differ materially from those expressed or

implied in these forward ‐looking statements. Forward ‐looking statements are not guarantees of

performance. Words such as “may”, “will”, “would”, “could”, “expect”, “believe”, “plan”, “anticipate”, “intend”,

“estimate”, “continue”, or the negative or comparable terminology, as well as terms usually used in the

future and the conditional, are intended to identify forward ‐looking statements. Information contained in

forward‐looking statements is based upon certain material assumptions that were applied in drawing a

conclusion or making a forecast or projection, including management’s perceptions of historical trends,

current conditions and expected future developments, results of further exploration work to define and

expand mineral resources, that exploration work will continue to show significant anomalous results in the

oxide, transition and sulphide horizons and indicate continuity near surface and along strike and, open to

the west along trend, that the gold mineralization continues to be associated with intense sericite and

chlorite alteration and be intrusion related with host sedimentary rocks, that the breccia continu es to be

defined to a vertical depth of 500 meters and at an average depth of 250 meters , as well as other

considerations that are believed to be appropriate in the circumstances. Osisko Development considers its

assumptions to be reasonable based on information currently available, but cautions the reader that their

assumptions regarding future events, many of which are beyond the control of Osisko Development, may

ultimately prove to be incorrect since they are subject to risks and uncertainties that affect Osisko

Development and its business. Such risks and uncertainties include, among others, risks relating to the

ability of exploration activities (including drill results) to accurately predict mineralization; errors in

management’s geological modelling; the ability of to complete further exploration activities, including

drilling; property and stream interests in the San Antonio gold project; the ability of the Corporation to obtain

required approvals; the results of exploration activities; risks relating to exploration, development and

mining activities; the global economic climate; metal prices; dilution; environmental risks; and community

and non-governmental actions and the responses of relevant governments to the COVID -19 outbreak and

the effectiveness of such responses.

For additional information with respect to these and other factors and assumptions underlying the forward ‐

looking statements made in this news release concerning Osisko Development, see the Filing Statement

available electronically on SEDAR (www.sedar.com) under Osisko Development's issuer profile. The

forward‐looking statements set forth herein concerning Os isko Development reflect management's

expectations as at the date of this news release and are subject to change after such date. Osisko

Development disclaims any intention or obligation to update or revise any forward- looking statements,

whether as a result of new information, future events or otherwise, other than as required by law.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in

the policies of the TSX Venture Exchange) accepts responsibility for the ad equacy or accuracy of

this news release. No stock exchange, securities commission or other regulatory authority has

approved or disapproved the information contained herein.

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Table 1: San Antonio Gold Project 2021 Length Weighted Drill Hole Gold and Silver Composites

from California Zone

HOLE ID FROM

(M) TO (M) LENGTH

(M) AU (G/T) AG (G/T)

CA-DD-21-020 159.40 166.35 6.95 1.19 1.25

Including 160.70 161.85 1.15 5.28 1.63

201.55 202.95 1.40 0.94 0.34

CA-DD-21-026 58.45 67.65 9.20 0.48 1.24

Including 64.70 66.15 1.45 1.49 2.47

90.75 91.55 0.80 0.71 2.24

124.45 164.40 39.95 0.63 0.90

Including 124.45 125.95 1.50 4.05 5.96

and 133.00 133.65 0.65 3.58 1.13

and 147.10 148.60 1.50 1.82 0.75

and 161.40 162.50 1.10 3.15 1.60

CA-DD-21-032 123.90 133.55 9.65 0.90 13.74

Including 127.55 129.05 1.50 1.82 28.20

and 129.05 130.55 1.50 1.29 6.48

and 132.05 133.55 1.50 1.21 5.96

CA-DD-21-037 29.00 30.35 1.35 1.38 0.89

86.40 98.30 11.90 1.50 13.96

Including 86.40 87.05 0.65 9.51 24.40

and 87.05 87.95 0.90 9.81 64.20

CA-DD-21-041 82.65 93.90 11.25 1.31 1.42

Including 84.90 86.40 1.50 1.49 2.81

and 86.40 87.80 1.40 5.48 3.44

and 92.40 93.90 1.50 2.17 1.36

114.90 122.40 7.50 0.55 0.82

Including 114.90 116.40 1.50 1.79 1.22

CA-DD-21-045 0.00 9.80 9.80 0.80 1.22

Including 5.25 8.25 3.00 2.14 1.57

29.55 36.00 6.45 0.64 1.55

Including 29.55 31.05 1.50 2.16 4.30

CA-DD-21-051 4.35 23.00 18.65 0.67 30.83

Including 9.85 11.35 1.50 1.20 4.75

and 12.85 14.35 1.50 1.23 9.07

and 14.35 15.85 1.50 1.11 127.00

and 17.35 18.85 1.50 1.35 70.00

38.10 51.90 13.80 0.58 5.38

Including 47.10 48.60 1.50 1.33 2.72

and 51.00 51.90 0.90 2.89 26.80

128.90 130.40 1.50 2.49 6.21

151.10 151.65 0.55 5.18 3.94

175.00 190.05 15.05 0.59 3.41

Including 187.85 188.95 1.10 1.11 2.43

and 188.95 190.05 1.10 1.27 2.83