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Osisko Development Intersects 20.40 G/T Au over 6.55 Meters, 117.00 G/T Au over 0.90 Meter and 155.50 G/T Au over 0.50 Meter ON Island Mountain

Drill Results

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OSISKO DEVELOPMENT INTERSECTS 20.40 G/T AU OVER 6.55 METERS, 117.00

G/T AU OVER 0.90 METER AND 155.50 G/T AU OVER 0.50 METER ON ISLAND

MOUNTAIN

MONTREAL, October 19, 2021 – Osisko Development Corp. (“Osisko Development” or the “Company”)

(TSX.V-ODV) is pleased to announce drilling results from the 2021 exploration and category conversion

drill program campaign at its Cariboo Gold Project (“ Cariboo”) in central British Columbia. A total of 6

diamond drill rigs are currently active on the Project.

Summary

• A total of 147,000 meters have been drilled thus far in 2021, of which 10,000 meters were drilled

at Mosquito and 58,000 drilled at Shaft.

• Recent assay results include holes IM-21-087 to IM -21-101 from Mosquito and Shaft Zones on

Island Mountain (Figure 1).

• IM-21-089 intersected 20.40 g/t Au over 6.55 meters at Shaft Zone and included high grade

samples of 92.30 g/t Au over 0.60 meter , 50.70 g/t Au over 0.60 meter , 28.10 g/t Au over 0.60

meter and 22.40 g/t Au over 1.25 meters.

• IM-21-090 tested both Shaft and Valley Zones, intersected multiple mineralized vein corridors in

both zones including 48.10 g/t Au over 2.40 meters with 117.0 g/t Au over 0.90 meter on the Shaft

Zone and 5.50 g/t Au over 12.25 meters including 54.5 g/t Au over 0.90 meter on the Valley Zone.

• Detailed drilling results and a drill hole location plan map are presented at the end of this release.

Assay Highlights

• 15.48 g/t Au over 3.40 meters in hole IM-21-088 including

• 28.80 g/t Au over 0.80 meter

• 20.40 g/t Au over 6.55 meters in hole IM-21-089 including

• 92.30 g/t Au over 0.60 meter and

• 50.70 g/t Au over 0.60 meter

• 48.10 g/t Au over 2.40 meters in hole IM-21-090 including

• 117.00 g/t Au over 0.90 meter

• 5.50 g/t Au over 12.25 meters in hole IM-21-090 including

• 54.50 g/t Au over 0.90 meter

• 97.40 g/t Au over 0.50 meter in hole IM-21-092

• 63.40 g/t Au over 0.50 meter in hole IM-21-092

• 9.85 g/t Au over 5.80 meters in hole IM-21-093 including

• 37.80 g/t Au over 1.15 meters

• 8.27 g/t Au over 6.30 meters in hole IM-21-097

• 34.03 g/t Au over 1.00 meter in hole IM-21-097 including

• 48.70 g/t Au over 0.50 meter

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• 49.40 g/t Au over 0.80 meter in hole IM-21-097

• 35.68 g/t Au over 2.25 meters in hole IM-21-097 including

• 155.50 g/t Au over 0.50 meter

• 6.23 g/t Au over 6.50 meters in hole IM-21-097 including

• 30.50 g/t Au over 1.00 meter

• 16.39 g/t Au over 2.70 meters in hole IM-21-098 including

• 52.60 g/t Au over 0.50 meter

• 7.61 g/t Au over 4.15 meters in hole IM-21-101

Chris Lodder, President of Osisko Development commented, “Drilling from the Shaft Zone over to the Valley

Zone has allowed us to intersect multiple deposits with one hole, and to explore along strike at Shaft zone

while testing down dip at Valley Zone. These recent results from holes IM-21-090 and IM-21-097 indicate

continuity between the two zones and significant expansion potential.

Vein corridors are defined as a high- density network of mineralized quartz veins within the axis of the last

folding event and hosted within a brittle meta-sandstone or calcareous meta-sandstone. Vein corridors are

modelled at a minimum thickness of 2 meters and average about 4.5 meters true width. Individual

mineralized veins within these corridors have widths varying from centimeters to several meters and strike

lengths from a few meters to over 50 meters. These corridors have been defined from surface to a vertical

depth averaging 300 meters and remain open for expansion at depth and along strike. Gold grades are

intimately associated with quartz vein-hosted pyrite as well as pyritic, intensely silicified wall rock haloes in

close proximity to the veins.

True widths are estimated to be 60% to 75% of reported core length intervals. Intervals not recovered by

drilling were assigned zero grade. Top cuts have not been applied to high grade assays. Complete assay

highlights are presented in Table 1, drill hole locations are listed in Table 2.

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Figure 1: Cariboo deposit areas overview map

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Figure 2: Mosquito Creek Zone select drilling highlights

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Figure 3: Shaft Zone select drilling highlights

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Qualified Persons

Per National Instrument 43-101 Standards of Disclosure for Mineral Projects, Maggie Layman, P.Geo. Vice

President Exploration of Osisko Development Corp. , is a Qualified Person and has prepared, validated,

and approved the technical and scientific content of this news release.

Quality Assurance – Quality Control

Once received from the drill and processed, all drill core samples are sawn in half, labelled and bagged.

The remaining drill core is subsequently stored on site at a secured facility in Wells, BC. Numbered security

tags are applied to lab shipments for chain of custody requirements. Quality control (QC) samples are

inserted at regular intervals in the sample stream, including blanks and reference materials with all sample

shipments to monitor laboratory performance. The QAQC program was designed and approved by Lynda

Bloom, P.Geo. of Analytical Solutions Ltd.

Drill core samples are submitted to ALS Geochemistry’s analytical facility in North V ancouver, British

Columbia for preparation and analysis. The ALS facility is accredited to the ISO/IEC 17025 standard for

gold assays and all analytical methods include quality control materials at set frequencies with established

data acceptance criteria. The entire sample is crushed, and 250 grams is pulverized. Analysis for gold is

by 50g fire assay fusion with atomic absorption (AAS) finish with a lower limit of 0.01 ppm and upper limit

of 100 ppm. Samples with gold assays greater than 100 ppm are re-analyzed using a 1,000g screen metallic

fire assay. A selected number of samples are also analyzed using a 48 multi -elemental geochemical

package by a 4- acid digestion, followed by Inductively Coupled Plasma Atomic Emission Spectroscopy

(ICP-AES) and Inductively Coupled Plasma Mass Spectroscopy (ICP-MS).

About Osisko Development Corp.

Osisko Development Corp. is well -capitalized and uniquely positioned as a premier gold development

company in North America to advance the Cariboo Gold Project and other Canadian and Mexican

properties, with the objective of becoming the next mid- tier gold producer. The Cariboo Gold Project,

located in central British Columbia, is Osisko Development's flagship asset with measured and indicated

resources of 21.44 Mt at 4.6 Au g/t for a total of 3.2 million ounces of gold and inferred resource of 21.69 Mt

at 3.9 Au g/t for a total of 2.7 million ounces of gold (see NI 43-101 Technical Report and mineral resource

estimate effective October 5th, 2020) . The considerable explorat ion potential at depth and along strike

distinguishes the Cariboo Gold Project relative to other development assets as does the historically low,

all-in discovery costs of US $19 per ounce. The Cariboo Gold Project is advancing through permitting as a

4,750 tonnes per day underground operation with a feasibility study on track for completion in the first half

of 2022. Osisko Development's project pipeline is complemented by potential near-term production targeted

from the San Antonio gold project, located i n Sonora Mexico and early exploration stage properties

including the Coulon Project and James Bay Properties located in Québec as well as the Guerrero

Properties located in Mexico. Osisko Development began trading on the TSX Venture Exchange under the

symbol “ODV” on December 2, 2020.

For further information, please contact Osisko Development Corp.:

Jean Francois Lemonde

VP Investor Relations

[email protected]

Tel: 514-299-4926

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Forward-looking Statements

Certain statements contained in this press release may be deemed “forward‐looking statements” within the

meaning of applicable Canadian and U.S. securities laws. These forward ‐looking statements, by their

nature, require Osisko Development to ma ke certain assumptions and necessarily involve known and

unknown risks and uncertainties that could cause actual results to differ materially from those expressed or

implied in these forward ‐looking statements. Forward ‐looking statements are not guarantees of

performance. Words such as “may”, “will”, “would”, “could”, “expect”, “believe”, “plan”, “anticipate”, “intend”,

“estimate”, “continue”, or the negative or comparable terminology, as well as terms usually used in the

future and the conditional, are intended to identify forward ‐looking statements. Information contained in

forward‐looking statements is based upon certain material assumptions that were applied in drawing a

conclusion or making a forecast or projection, including management’s perceptions of historical trends,

current conditions and expected future developments, including with respect to results of further exploration

work to define and expand mineral resources, expected conclusions of optimization studies, that vein

corridors continue to be defined as a high-density network of mineralized quartz within the axis of the last

folding event and hosted within the sandstones and that the deposit remains open for expansion at depth

and down plunge, as well as other considerations that are believed to be appropriate in the circumstances.

Osisko Development considers its assumptions to be reasonable based on information currently available,

but cautions the reader that their assumptions regarding future events, many of which are beyond the

control of Osisko Development, may ultimately prove to be incorrect since they are subject to risks and

uncertainties that affect Osisko Development and its business. Such risks and uncertainties include, among

others, risks relating to the ability of exploration activities (including drill results) to accurately predict

mineralization; errors in management’s geological modelling; the ability of to complete further exploration

activities, including drilling; property and royalty interests in the Cariboo gold deposit; the ability of the

Corporation to obtain required approvals; the results of exploration activities; risks relating to mining

activities; the global economic climate; metal prices; dilution; environmental risks; and community and non-

governmental actions and the responses of relevant governments to the COVID -19 outbreak and the

effectiveness of such responses.

For additional information with respect to these and other factors and assumptions underlying the forward‐

looking statements made in this news release concerning Osisko Development, see the Filing Statement

available electronically on SEDAR (www.sedar.com) under Osisko Development's iss uer profile. The

forward‐looking statements set forth herein concerning Osisko Development reflect management's

expectations as at the date of this news release and are subject to change after such date. Osisko

Development disclaims any intention or obligation to update or revise any forward- looking statements,

whether as a result of new information, future events or otherwise, other than as required by law.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in

the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of

this news release. No stock exchange, securities commission or other regulatory authority has

approved or disapproved the information contained herein.

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Table 1: Cariboo Gold Project 2021 Length Weighted Drill Hole Gold Composites

HOLE ID FROM M TO (M) LENGTH

(M) AU (G/T) TARGET

IM-21-087 10.30 11.50 1.20 3.22 Shaft

113.50 114.00 0.50 7.94

133.50 138.00 4.50 4.22

Including 133.50 134.45 0.95 7.37

and 137.35 138.00 0.65 16.90

162.00 162.75 0.75 4.00

IM-21-088 154.00 155.00 1.00 5.75 Mosquito

172.00 174.00 2.00 6.37

Including 172.00 173.00 1.00 8.16

and 173.00 173.50 0.50 7.90

205.80 206.30 0.50 4.37

209.60 213.00 3.40 15.48

Including 210.35 211.00 0.65 17.15

and 211.00 211.50 0.50 15.75

and 211.50 212.30 0.80 28.80

238.90 239.40 0.50 19.85

260.00 260.65 0.65 5.98

268.20 268.90 0.70 8.10

274.40 274.90 0.50 3.18

307.40 307.90 0.50 21.70

314.00 314.55 0.55 3.46

IM-21-089 12.00 12.85 0.85 5.52 Shaft

31.20 37.75 6.55 20.40

Including 31.20 31.80 0.60 92.30

and 31.80 32.40 0.60 50.70

and 34.40 35.00 0.60 28.10

and 35.50 36.75 1.25 22.40

42.60 43.35 0.75 5.98

44.60 45.10 0.50 4.18

180.45 181.70 1.25 3.99

214.30 214.90 0.60 14.65

IM-21-090 200.60 203.00 2.40 48.10 Shaft

Including 201.50 202.40 0.90 117.00

288.10 291.30 3.20 4.39

Including 288.10 289.50 1.40 9.46

303.90 304.90 1.00 3.56

311.15 312.00 0.85 13.15

342.50 343.10 0.60 5.34

386.00 388.00 2.00 6.16 Valley

Including 386.95 387.45 0.50 22.90

400.50 406.10 5.60 4.71

Including 400.50 401.25 0.75 7.16