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Osisko Development Intersects 15.87 G/T Au over 10.45 Meters and 93.30 G/T Au over 0.70 Meter at Valley Zone

Drill Results

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OSISKO DEVELOPMENT INTERSECTS 15.87 G/T AU OVER 10.45 METERS AND

93.30 G/T AU OVER 0.70 METER AT VALLEY ZONE

MONTREAL, Nov 2 4, 2021 – Osisko Development Corp. (“Osisko Development” or the “ Company”)

(TSX.V-ODV) is pleased to announce drilling results from the 2021 exploration and category conversion

drill program campaign at its Cariboo Gold Project (“Cariboo”) in central British Columbia.

Summary

• A total of 152,000 meters were drilled in 2021. Of that, 50,000 meters were drilled in 109 holes in

the Valley Zone Deposit.

• Recent assay results include holes CM-21-044 to CM-21-061 (Figures 1 and 2).

• CM-21-044 assayed 15.87 g/t Au over 10.45 meters including samples that assayed 66.20 g/t Au

over 0.75 meter, 81.90 g/t Au over 0.65 meter and 62.30 g/t Au over 0.80 meter increasing

confidence in an inferred vein corridor.

• CM-21-051 intersected a vein corridor and assayed 28.45 g/t Au over 4.10 meters including high

grade samples of 51.70 g/t Au over 0.50 meter, 67.80 g/t Au over 0.50 meter and 68.90 g/t Au

over 0.50 meter

• New mineralization was intersected across multiple mineralized vein corridors in holes CM-21-049:

63.2 g/t Au over 0.50 meters, 15.68 g/t Au over 3.0 meters and CM-21-059 intersected some of

the deepest anomalies at Valley to date, including 9.65 g/t Au over 4.0 meters including a sample

of 48.0 g/t Au over 0.75 meters, 500 meters from surface and 80 meters along strike from any

modelled vein corridors with significant potential to expand in the surrounding untested sandstone

(Figure 3).

Chris Lodder, President of Osisko Development commented, “Many of the holes in the category conversion

program have intersected new vein corridors or expanded up dip and along strike. Hole CM- 21-059

provides further indication that we have significant potential within our current deposit areas. These

intercepts show the deposit continues down plunge in the sandstone and open for several hundred meters

to the northwest and up dip as shown in Figure 3.”

Assay Highlights

• 15.87 g/t Au over 10.45 meters in hole CM-21-044 including

• 66.20 g/t Au over 0.75 meter and

• 81.90 g/t Au over 0.65 meter and

• 62.30 g/t Au over 0.80 meter

• 19.95 g/t Au over 3.85 meters in hole CM-21-045 including

• 82.40 g/t Au over 0.50 meter

• 12.12 g/t Au over 6.12 meters in hole CM-21-045 including

• 93.30 g/t Au over 0.70 meter

• 57.60 g/t Au over 0.50 meters in hole CM-21-047

• 63.20 g/t Au over 0.50 meters in hole CM-21-049

• 15.68 g/t Au over 3.00 meters in hole CM-21-049 including

• 82.80 g/t Au over 0.50 meter

• 28.45 g/t Au over 4.10 meters in hole CM-21-051 including

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• 51.70 g/t Au over 0.50 meter and

• 67.80 g/t Au over 0.50 meter and

• 68.90 g/t Au over 0.50 meter

• 93.60 g/t Au over 0.55 meter in hole CM-21-055

• 27.24 g/t Au over 3.50 meters in hole CM-21-056 including

• 74.10 g/t Au over 1.20 meters

• 11.12 g/t Au over 5.75 meters in hole CM-21-058

• 9.65 g/t Au over 4.00 meters in hole CM-21-059 including

• 48.0 g/t Au over 0.75 meter

• 19.37 g/t Au over 2.30 meters in hole CM-21-061 including

• 29.80 g/t Au over 1.30 meters

Mineralized quartz veins on Cariboo are overall sub- vertical dip and northeast strike. Vein corridors are

defined as a high- density network of mineralized quartz veins within the axis of the last folding event and

hosted within a brittle meta- sandstone or calcareous meta- sandstone. Vein corridors are modelled at a

minimum thickness of 2 meters and average about 4.5 meters true width. Individual mineralized veins within

these corridors have widths varying from centimeters to several meters and strike lengths from a few meters

to over 50 meters. These corridors have been defined from surface to a vertical depth averaging 300 meters

and remain open for expansion at depth and along strike. Gold grades are intimately associated with quartz

vein-hosted pyrite as well as pyritic, intensely silicified wall rock haloes in close proximity to the veins.

True widths are estimated to be 60% to 75% of reported core length intervals. Intervals not recovered by

drilling were assigned zero grade. Top cuts have not been applied to high grade assays. Complete assay

highlights are presented in Table 1, drill hole locations are listed in Table 2.

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Figure 1: Cariboo deposit areas overview map

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Figure 2: Valley Zone select drilling

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Figure 3: Valley zone Cross section with select drillhole highlights

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Qualified Persons

Per National Instrument 43-101 Standards of Disclosure for Mineral Projects, Maggie Layman, P.Geo. Vice

President Exploration of Osisko Development Corp. , is a Qualified Person and has prepared, validated,

and approved the technical and scientific content of this news release.

Quality Assurance – Quality Control

Once received from the drill and processed, all drill core samples are sawn in half, labelled and bagged.

The remaining drill core is subsequently stored on site at a secured facility in Wells, BC. Numbered security

tags are applied to lab shipments for chain of custody requirements. Quality control (QC) samples are

inserted at regular intervals in the sample stream, including blanks and reference materials with all sample

shipments to monitor laboratory performance. The QAQC program was designed and approved by Lynda

Bloom, P.Geo. of Analytical Solutions Ltd.

Drill core samples are submitted to ALS Geochemistry’s analytical facility in North Vancouver, British

Columbia for preparation and analysis. The ALS facility is accredited to the ISO/IEC 17025 standard for

gold assays and all analytical methods include quality control materials at set frequencies with established

data acceptance criteria. The entire sample is crushed, and 250 grams is pulverized. Analysis for gold is

by 50g fire assay fusion with atomic absorption (AAS) finish with a lower limit of 0.01 ppm and upper limit

of 100 ppm. Samples with gold assays greater than 100 ppm are re-analyzed using a 1,000g screen metallic

fire assay. A selected number of samples are also analyzed using a 48 multi -elemental geochemical

package by a 4- acid digestion, followed by Inductively Coupled Plasma Atomic Emission Spectroscopy

(ICP-AES) and Inductively Coupled Plasma Mass Spectroscopy (ICP-MS).

About Osisko Development Corp.

Osisko Development Corp. is uniquely positioned as a premier gold development company in North

America to advance the Cariboo Gold Project and other Canadian and Mexican properties, with the

objective of becoming the next mid- tier gold producer. The Cariboo Gold Project, located in central British

Columbia, is Osisko Development's flagship asset with measured and indi cated resources of 21.44 Mt at

4.6 Au g/t for a total of 3.2 million ounces of gold and inferred resource of 21.69 Mt at 3.9 Au g/t for a total

of 2.7 million ounces of gold (see NI 43- 101 Technical Report and mineral resource estimate effective

October 5th, 2020) . The considerable exploration potential at depth and along strike distinguishes the

Cariboo Gold Project relative to other development assets as does the historically low, all-in discovery costs

of US $19 per ounce. The Cariboo Gold Project is advancing through permitting as a 4,750 tonnes per day

underground operation with a feasibility study on track for completion in the first half of 2022. Osisko

Development's project pipeline is complemented by potential near -term production targeted from the San

Antonio gold project, located in Sonora Mexico and early exploration stage properties including the Coulon

Project and James Bay Properties located in Québec as well as the Guerrero Properties located in Mexico.

Osisko Development began trading on the TSX Venture Exchange under the symbol “ ODV” on

December 2, 2020 and the Company’s 14,789,373 outstanding share purchase warrants were listed on the

TSX Venture Exchange under the symbol “ODV.WT” on October 25, 2021.

For further information, please contact Osisko Development Corp.:

Jean Francois Lemonde

VP Investor Relations

[email protected]

Tel: 514-299-4926

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Forward-looking Statements

Certain statements contained in this press release may be deemed “forward‐looking statements” within the

meaning of applicable Canadian and U.S. securities laws. These forward ‐looking statements, by their

nature, require Osisko Development to make certain assumptions and necessarily involve known and

unknown risks and uncertainties that could cause actual results to differ materially from those expressed or

implied in these forward ‐looking statements. Forward ‐looking statements are not guarantees of

performance. Words such as “may”, “will”, “would”, “could”, “expect”, “believe”, “plan”, “anticipate”, “intend”,

“estimate”, “continue”, or the negative or comparable terminology, as well as terms usually used in the

future and the conditional, are intended to identify forward ‐looking statements. Information contained in

forward‐looking statements is based upon certain material assumptions that were applied in drawing a

conclusion or making a forecast or projection, including management’s perceptions of historical trends,

current conditions and expected future developments, results of further exploration work to define and

expand mineral resources, expected conclusions of optimization studies, that vein corridors continue to be

defined as a high-density network of mineralized quartz within the axis of the last folding event and hosted

within the sandstones and that the deposit remains open for expansion at depth and down plunge, as well

as other considerations that are believed to be appropriate in the circumstances. Osisko Development

considers its assumptions to be reasonable based on information currently available, but cautions the

reader that their assumptions regarding future events, many of which are beyond the control of Osisko

Development, may ultimately prove to be incorrect since they are subject to risks and uncertain ties that

affect Osisko Development and its business. Such risks and uncertainties include, among others, risks

relating to the ability of exploration activities (including drill results) to accurately predict mineralization;

errors in management’s geologi cal modelling; the ability of to complete further exploration activities,

including drilling; property and royalty interests in the Cariboo gold deposit; the ability of the Corporation to

obtain required approvals; the results of exploration activities; ri sks relating to mining activities; the global

economic climate; metal prices; dilution; environmental risks; and community and non- governmental

actions and the responses of relevant governments to the COVID -19 outbreak and the effectiveness of

such responses.

For additional information with respect to these and other factors and assumptions underlying the forward ‐

looking statements made in this news release concerning Osisko Development, see the Filing Statement

available electronically on SEDAR (www.sedar .com) under Osisko Development's issuer profile. The

forward‐looking statements set forth herein concerning Osisko Development reflect management's

expectations as at the date of this news release and are subject to change after such date. Osisko

Development disclaims any intention or obligation to update or revise any forward- looking statements,

whether as a result of new information, future events or otherwise, other than as required by law.

Neither the TSX Venture Exchange nor its Regulation Services Pr ovider (as that term is defined in

the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of

this news release. No stock exchange, securities commission or other regulatory authority has

approved or disapproved the information contained herein.

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Table 1: Cariboo Gold Project 2021 Length Weighted Drill Hole Gold Composites

HOLE ID FROM M TO (M) LENGTH

(M) AU (G/T)

CM-21-044 293.00 303.45 10.45 15.87

Including 294.05 294.55 0.50 12.10

and 299.80 300.55 0.75 66.20

and 301.40 302.05 0.65 81.90

and 302.65 303.45 0.80 62.30

307.85 308.50 0.65 3.40

445.65 447.35 1.70 4.54

456.80 457.30 0.50 7.07

475.60 476.10 0.50 3.88

502.70 507.80 5.10 3.61

Including 502.70 503.65 0.95 8.03

and 503.65 504.60 0.95 5.62

and 507.05 507.80 0.75 7.09

590.55 591.40 0.85 4.13

605.25 606.45 1.20 5.16

615.05 615.55 0.50 3.51

CM-21-045 37.30 37.80 0.50 10.65

70.05 70.65 0.60 3.29

127.80 128.35 0.55 6.91

150.80 151.30 0.50 3.10

160.30 164.15 3.85 19.95

Including 160.30 160.80 0.50 82.40

and 160.80 161.70 0.90 14.15

and 161.70 162.20 0.50 36.10

207.70 212.75 5.05 2.98

Including 207.70 208.20 0.50 17.20

and 210.70 211.25 0.55 8.30

233.00 233.50 0.50 35.00

241.00 247.20 6.20 12.12

Including 241.55 242.25 0.70 93.30

and 246.60 247.20 0.60 10.75

271.30 271.80 0.50 20.60

CM-21-046 77.90 79.00 1.10 12.25

77.90 78.40 0.50 24.50

146.20 146.70 0.50 4.51

151.20 152.20 1.00 10.43

160.70 161.75 1.05 7.74

179.70 180.20 0.50 5.16

199.00 201.20 2.20 4.42

222.50 225.50 3.00 3.46

Including 222.50 223.00 0.50 16.75

245.75 246.75 1.00 3.69

Including 245.75 246.25 0.50 6.05

264.00 265.00 1.00 5.62

303.30 303.80 0.50 4.88