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Mako Mining Receives Drilling Permit at Potrerillos

Permits & Approvals

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595 Burrard Street, Suite 2833

Vancouver, BC V7X 1K8

Tel: (604) 646-1580

www.makominingcorp.com

TSX-V: MKO | OTCQX: MAKOF

November 19, 2021

TSX-V: MKO; OTCQX: MAKOF

Mako Mining Receives Drilling Permit at Potrerillos

Mako Mining Corp. (TSX-V: MKO; OTCQX: MAKOF) (“Mako” or the “Company”) is pleased to report that the

Ministry of Environmental and Natural Resources (“MARENA”) has granted an exploration permit to the Company

for the Potrerillos concession acquired in December 2019.

Starting from November 15, 2021, the permit is valid for 10 years and is renewable for up to an additional 20 years.

The Company is now permitted to drill up to 800,000 meters (“m”) as follows: 250,000 m of diamond drilling ;

250,000 m of reverse circulation drilling ; and 300,000 m of blast hole drilling. The Company is also permitted to

carry out up to 12,000 m of trenching.

Additionally, as of November 12, 2021, all legal documents and procedures, including the public consultation for the

La Segoviana concession, located northeast of Potrerillos, are complete. The Company awaits MARENA’s approval

of this additional exploration permit, which is expected over the course of the next 45 days.

Akiba Leisman, Chief Executive Officer of Mako states that, “I would personally like to thank MARENA on behalf

of our team for granting this permit. This is yet another example of why Nicaragua is a mining friendly jurisdiction.

Reconnaissance exploration work to date indicates that Potrerillos is the direct strike extension of the San Albino

gold deposit, and the receipt of these permits allows us to begin drill testing the approximately 3.5 kilometers of strike

potential. The district potential of San Albino is becoming clearer, and these permits will allow us to begin the

process of discovery on parts of our concessions that have never been drilled before.”

See the map below titled “Concessions Map” for more details on the location of the Potrerillos concession relative

to the San Albino gold deposit and the three other concessions that comprise Mako’s approximately 188 square

kilometers land package in northern Nicaragua.

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On behalf of the Board,

Akiba Leisman

Chief Executive Officer

About Mako

Mako Mining Corp. is a publicly listed gold mining, development and exploration company. The Company operates

the high-grade San Albino gold mine in Nueva Segovia, Nicaragua, which ranks as one of the highest-grade open pit

gold mines globally. Mako’s primary objective is to operate San Albino profitably and fund exploration of

prospective targets on its district-scale land package.

For further information: Mako Mining Corp., Akiba Leisman, Chief Executive Officer, Telephone: 203-862-7059,

E-mail: [email protected] or visit our website at www.makominingcorp.com and SEDAR

www.sedar.com.

Forward-Looking Information: Some of the statements contained herein may be considered “forward -looking information”

within the meaning of applicable securities laws. The forward-looking information contained herein is based on the Company’s

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current plans, expectations and assumptions, and includes, without limitation, information related to plans to begin drill testing

the approximately 3.5 kilometers of strike potential to confirm continuity of mineralization from San Albino and a process of

discovery on parts of our concessions that have never been drilled before; and the expectation that we will obtain from MARENA

a permit for the La Segoviana concession over the course of the next 45 days; Such forward-looking information is subject to a

variety of risks and uncertainties which could cause actual events or results to differ materially from those reflected in the

forward-looking information, including, without limitation , that the Company does not continue to find positive results from its

proposed drilling on the Potrerillos concession; that exploration and assay resu lts do not confirm continuity of mineralization

as expected; that MARENA does not approve and issue a permit for the La Segoviana concession within the timeframe expected,

or at all; political risks and uncertainties involving the Company’s exploration properties; the inherent uncertainty of cost

estimates and the potential for unexpected costs and expense; commodity price fluctuations and other risks and uncertainties as

disclosed in the Company’s public disclosure filings on SEDAR at www.sedar.com. Such information contained herein represents

management’s best judgment as of the date hereof, based on information currently available and is included for the purposes o f

providing investors with the Company’s plans and expectations regarding the exploration of the Potrerillos concession and the

potential for expansion of the mineralization at San Albino, and may not be appropriate for other purposes. Mako does not

undertake to update any forward-looking information, except in accordance with applicable securities laws.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture

Exchange) accepts responsibility for the adequacy or accuracy of this release.