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IsoEnergy Winter Drilling Intersects Elevated Radioactivity in Multiple Holes, Including 30,050 cps over 1.0 Metre, in a Newly Reinterpreted Fault Zone on the South Trend of the Hurricane Deposit

Exploration Programs

IsoEnergy Winter Drilling Intersects Elevated Radioactivity in Multiple Holes,

Including 30,050 cps over 1.0 Metre, in a Newly Reinterpreted Fault Zone on the

South Trend of the Hurricane Deposit

Toronto, ON, April 7, 2026 – IsoEnergy Ltd. (“IsoEnergy” , or “The Company”) (NYSE American: ISOU;

TSX: ISO ) is pleased to announce results from its recently completed 2026 winter exploration drilling

program at the Larocque East project (the “ Project”), home to the high-grade Hurricane deposit

(“Hurricane” or the “Deposit”), in the eastern Athabasca Basin, Canada. The program was expanded based

on encouraging results, increasing from an initial plan of 1 3 diamond drill holes totaling 5,200 m to 17

diamond drill holes totaling 6,804 m, targeting potential resource expansion at the Deposit and testing

greenfield targets up to three kilometres east along the Larocque Trend (“Larocque Trend”).

Hurricane hosts a current Mineral Resource of 48.6 Mlb U3O8 at 34.5% U3O8 Indicated, and 2.7 Mlb U3O8 at

2.2% U 3O8 Inferred (See “Qualified Person Statement” below) . The Project benefits from excellent

infrastructure, located approximately 40 km northwest of the McClean Lake mill, and features relatively

shallow mineralization at approximately 325 m depth, supporting efficient exploration and future

development optionality. The Deposit is located on the Larocque Trend, an important regional structure

that also hosts other notable high-grade occurrences including those on Cameco and Orano’s Dawn Lake

joint venture.

Highlights

• Additional mineralized fault strands have been identified across the width of the Hurricane

South Trend, highlighting a broader and more prospective corridor than previously interpreted,

with potential for additional zones within underexplored areas.

• Drill hole LE26-248, drilled within the low -grade resource envelope (Figures 1, 2 and 3 ),

intersected strongly elevated radioactivity returning an average RS -125 spectrometer reading

on drill core of 30,050 counts per second (“cps”) over 1.0 m (local off-scale readings of >65,500

cps), within a broader zone of 11,275 cps over 3.5 m, in the newly reinterpreted L fault zone

within the South Trend.

• Mineralization has now been intersected in multiple holes along the South Trend up to 540 m

east of the Deposit footprint (Figure 1). Strongly elevated radioactivity intersected in multiple

2026 holes builds on past results in demonstrating the growing scale and prospectivity of this

trend:

− LE26-241 (100 m east of LE26-248): Intersected strongly elevated radioactivity in the

lower 8 m of sandstone above the unconformity at 325.9 m, including 3,712 cps over 0.5

m.

− LE26-243 (180 m east of LE26-248): Intersected an average of 10,000 cps over a 0.5 m

within an interval of elevated radioactivity in the lower 6 m of sandstone above the

unconformity at 328.9 m.

− LE26-234 (560 m east of LE26-248): Intersected two intervals of elevated radioactivity.

o A 1.5 m interval, including 6,450 cps over 0.5 m, within altered lower sandstone

(moderate to strong clay alteration, quartz dissolution, and faul ts) located 26 m

above the unconformity at 358.9 m; and

o A 2.5 m interval in the basal sandstone immediately above the unconformity,

including 1,270 cps over 0.5 m.

• Geochemical results are pending as IsoEnergy prepares for summer drilling.

− All samples from the winter drill program have been submitted to the Saskatchewan

Research Council Geoanalytical Laboratory, with assay results anticipated in due course.

Table 1: Selected Radioactivity Highlights, 2026 Winter Drilling Program, Larocque East Project1

1. See Table 2 for a listing of individual 0.5 m mineralized intervals defined as intervals over which average RS -125

handheld spectrometer readings on drill core exceeded 350 cps.

2. Radioactivity is total gamma from drill core measured with an RS-125 hand-held spectrometer.

3. Individual 0.5 m interval cps values reported throughout this press release are averages of three readings taken

over the 0.5 m interval.

4. Measurements of total gamma cps on drill core are an indication of uranium content but may not correlate with

uranium chemical assays.

Dan Brisbin, Vice President of Exploration, stated, "The 30,050-cps result in LE26 -248, combined with

elevated radioactivity confirmed in step-out holes up to 560 metres along strike to the east, continues to

highlight the prospectivity of the Hurricane South Trend. Results to date are being used by our Project

team to reinterpret the faults that control uranium mineralizatio n along the South Trend and suggest

potential for additional mineralization in areas that remain underexplored. We look forward to following

up on these results with further drilling."

Philip Williams, CEO and Director, commented, "I'd like to congratulate the entire Larocque East technical

team on a highly successful winter drill program driven by a rigorous geological approach . T he team

delivered an expanded program, safely and efficiently, producing some of the most encouraging results

we've seen along the South Trend and demonstrating the scale of the opportunity in this underexplored

corridor. Upon receipt of assay results, the team will design an aggressive follow -up program to further

test the South Trend as part of our 2026 summer exploration drilling."

Hole From To Lengh Radioactivity 2-4

ID (m) (m) (m) (CPS)

LE26-234 332.0 332.5 0.5 6,450

358.0 358.5 0.5 1,270

LE26-239 336.8 337.8 1.0 2,747

LE26-241 317.5 318 0.5 3,712

LE26-243 326.5 327 0.5 10,000

333.5 334 0.5 1,800

LE26-244 332.0 332.5 0.5 1,150

LE26-248 328 331.5 3.5 11,275

incl. 329.5 330.5 1.0 30,050

LE26-249 330 330.5 0.5 2,000

Figure 1 – 2026 winter drill holes in the Hurricane Deposit area. Mineralization highlights are U3O8 for

selected pre-2026 drill holes referred to in the text and cps measured on drill core with an RS-125

handheld spectrometer for 2026 drill holes.

Resource Expansion Targets at Hurricane

Winter drilling focused on resource expansion targets along the North and South trends that flank the

Hurricane deposit (Figure 1). These trends are situated within a low seismic velocity anomaly identified

by ambient noise tomography (“ANT”), which is interpreted to map the prospective Hurricane alteration

zone. Uranium mineralization was intersected on both trends in 2026 drill holes, building on intersections

along these two trends in 2025. Additionally, three drill holes tested targets up to three kilometres along

trend to the east of the Hurricane deposit.

South Trend

The Hurricane South Trend is a compelling exploration trend with mineralization intersected in multiple

holes over a 540 m strike length to the east of the Deposit . Winter 2026 drilling continued t o test the

South Trend of the Deposit and along strike to the east , building on positive results from 2025 that

intersected mineralization near the unconformity in drill holes LE25 -207 and LE25-210, and in previous

holes LE21-101 and LE22-115A (see press release dated December 3, 2025). Results from the 2026 winter

drilling program continue to demonstrate the potential for a significant unconformity -style uranium

discovery along this trend.

Hurricane Footprint on the South Trend

Two holes, LE26 -244 and LE26 -248, were drilled within the footprint of the low -grade zone in the

southwestern portion of the Deposit, with LE26-249 drilled approximately 40 m along strike to the east of

LE26-248 to follow up on strongly elevated radioactivity intersected in LE26-248 on the newly redefined

L Fault Zone (Figure 3). The L Fault Zone is the southernmost east -striking structure recognized at

Hurricane, consisting of one or more fault strands within the South Trend. Exploration on the South Trend

has historically focused on the J and K faults that control mineralization in the southern high-grade lens

of the Hurricane deposit. The 30,050 cps result in LE26-248 highlights the prospectivity of the L Fault Zone,

and future drilling will look to better define its geometry, controls on mineralization, and continuity along

strike.

LE26-248 returned 30,050 cps over 1.0 m (with local off-scale peak readings >65,500 cps) straddling the

unconformity at 330. 2 m (Figure 2) within a broader interva l that averaged 11,275 cps over 3.5 m .

Anomalous radioactivity exceeding 400 cps commences within the sooty pyrite zone in the basal

sandstone, extending into the graphitic pelite below.

Figure 2 – LE26-248 drill core averaging 30,050 cps over 1.0 m as measured by RS-125 spectrometer

within a 3.5 m interval in which average 0.5 m interval radioactivity ranges from 445 cps to 30,100 cps.

The yellow line marks the unconformity, obscured by alteration and mineralization. White lines

indicate the assay sample intervals which also correspond to the 0.5 m intervals over which average

cps is measured (labelled in white text). Red lines indicate the extent of radioactivity >350 cps. The

core from this interval is considered as “mineralized” and split and submitted for U3O8 assay along

with two 0.5 m long samples “shoulder” samples above and below the mineralized interval.

The sandstone column from 143.5 m to the unconformity is characterized by strongly pervasive bleaching

associated with illitic and kaolinitic clay alteration, indicative of a well -developed hydrothermal system

characteristic of unconformity -style uranium d eposits in the Athabasca Basin. Two zones of structural

disruption were intersected: a 14.3 m (drill width) wide fault zone at 251.7 m characterized by intermittent

broken core and quartz dissolution, preceded above by a weak to moderate pervasive hematite overprint

from 143.5 m; and a 13.3 m (drill width) wide fault zone at 303.7 m characterized by broken, blocky and

friable sandstone with a strong hydrothermal hematite overprint transitioning to a pervasive sooty pyrite

overprint at 312.1 m that extends to the unconformity.

Figure 3 – Hurricane deposit cross section 4485E showing location of strongly elevated radioactivity

intersected at the unconformity in 2026 drill hole LE26-248 along the newly reinterpreted L Fault Zone

with the Hurricane South Trend. The cross section is drawn looking east and depicts geology from

approximately 100 m above the unconformity to approximately 150 m below the unconformity.

LE26-244 returned up to 1,150 cps over 0.5 m within a broader interval averaging 717 cps over 1.5 m,

associated with sooty pyrite in the basal sandstone immediately above the unconformity at 332.8 m.

The sandstone column is characterized by progressive bleaching and illitic clay alteration from surface,

with three discrete zones of structural disruption: an 8.6 m (drill width) wide fault zone associated with

strong pervasive limonite staining at 164.4 m, a 22.7 m (drill width) wide fault zone characterized by quartz

dissolution and broken and blocky core from 276.9 to 299.6 m, and a 10.7 m (drill width) wide fault zone

from 313.0 to 323.7 m associated with a strong hydrothermal hematite overprint. Below the lowermost

fault zone, the sandstone is grey and reduced with a pervasive sooty pyrite overprint, transitioning to very

reduced dark grey to black core from 329.8 m to the unconformity. Graphitic pelite was intersected in the

basement below.

While the radioactivity returned in LE26 -244 is lower grade than the adjacent LE26 -248, the well -

developed alteration, the degree of structural disruption, and sooty pyrite reduction front at the

unconformity contact remain highly prospective and warrant further evaluation.

LE26-249 was drilled approximately 40 m along strike to the east of LE26-248 to follow up on the strongly

elevated radioactivity intersected in that hole. The hole intersected a thick sequence of hydrothermally

altered sandstone, with moderate bleaching commencing at 119.0 m and clay alteration predominantly

illitic from 100.0 m with minor kaolinite to the unconformity. Strong bleaching with a pervasive interstitial

white clay overprint commences at 261.5 m, persisting to the unconformity, associated with a fault zone

from 261.7 to 263.4 m characterized by discrete isolated faults with quartz dissolution. A second fault

zone from 307.8 to 315.7 m contains multiple clay gouges ranging from 0.2 to 0.5 m in width, associated

with a hydrothermal hematite overprint. Trac e sooty pyrite alteration was intersected from 326.0 m,

intensifying to moderate sooty pyrite from 330.0 to 330.5 m , with associated 2,000 cps over 0.5 m,

immediately above the unconformity at 330.8 m. Graphitic pelite was intersected in the basement below

the unconformity.

The position of the fault zones within the sandstone column rather than at the unconformity suggests the

hole did not intersect the optimal target and was likely drilled slightly into the footwall of the prospective

structure. The alteration, structural setting, and weak mineralization at the unconformity are encouraging

and indicate that there is still potential and warrant further evaluation.

South Trend Step Out

Drill holes LE26-241, LE26-243, and LE26-247 were drilled to test the South Trend between the southern

portion of the Deposit and a zone of mineralization intersected in LE21-101, LE22-115A, and LE25 -207

approximately 240 m east of the deposit (Figure 1). LE26-241 intersected strongly elevated radioactivity

in the lower eight metres of sandstone above the unconformity at 325.9 m, including an average RS -125

reading over 0.5 m of 3,712 cps . LE26-243 intersected strongly elevated radioactivity in the lower six

metres of sandstone above the unconformity at 328.9 m, including a maximum of 10,000 cps over a 0.5

m interval. LE26-247 intersected a well-developed alteration zone and structural setting consistent with

the South Trend, however no significant radioactivity was returned, likely reflecting a footwall position

relative to the optimal target.

LE26-241 intersected elevated radioactivity in two intervals within the lower 8 m of sandstone above the

unconformity at 325.9 m , an upper interval between 317.5 m and 321.0 m with 0.5 m average RS-125

values ranging from 297 cps to 3,712 cps within a zone of strong hydrothermal hematite , and a lower

interval from 323.0 m to 325.5 m ranging from 342 cps to 862 cps within reduced sandstone immediately

above the unconformity. The sandstone column is moderate ly to strongly bleached with predominantly

illitic clay alteration from 128.0 m . A broad zone of structural disruption from 287.0 to 322.0 m is

associated with strong hydrothermal hematite and discrete clay gouges to the unconformity. Pegmatite

was intersected immediately below the unconformity, contacting graphitic pelite at 330.0 m.

LE26-243 intersected strongly elevated radioactivity immediately above the unconformity at 328.9 m,

with a peak RS -125 readings averaging 10,000 cps over 0.5 m from 326.5 m to 327.0 m within a zone

overprinted by strong hydrothermal hematite, correlating with anomalous readings ranging from 145 to

10,000 cps extending over approximately 6.0 m to the unconformity . The sandstone column is bleached

from 263.4 m with predominantly illitic clay alteration, and a zone of structural disruption from 284.0 to

296.2 m characterized by quartz dissolution and clay -infilled fractures. Below this , strong hydrothermal

hematite transitions to a sooty pyrite overprint from 327.0 m to the unconformity. A secondary anomaly

of 1,800 cps was returned between 333.5 m and 334.0 m within a basement shear zone associated with

weak hydrothermal hematite, suggesting uranium mobility extends into the basement.

LE26-247 intersected a well-developed alteration zone with predominantly illitic clay from 130.0 m ,

bleaching from 165.0 m becoming strongly bleached below 234.3 m, and four fault zones below 228.0 m

characterized by quartz dissolution, clay -infilled fractures, and fracture -controlled limonite . Graphitic

pelite with several shear zones was intersected below the unconformity at 323.8 m . No significant

radioactivity was returned above background. The degree of structural disruption in the lower sandstone

column suggests the hole was drilled slightly into the footwall of the prospective structure, however the

alteration s ignature, structural setting, and graphitic basement are consistent with the key elements

observed in mineralized holes along the South Trend and warrant further evaluation.

LE26-246 was drilled to test for the potential extension of the southwestern boundary of the Hurricane

deposit south of where currently interpreted as mineralization in the southernmost previous drill hole,

LE21-103. Elevated radioactivity was not intersected but mineral spectrometry results indicate that the

entire sandstone column is strongly illitic, with lesser, localized dickite. This prospective clay mineralogy

corresponds to the observation that bleached intervals with desilicification and clay alteration focused

along numerous fault and fracture zones are present throughout the sandstone column. This degree of

structural disruption and alteration is consistent with LE26-246 traversing the up -dip expression of the

Hurricane alteration zone and intersecting the unconformity only about 20 m south of the interpreted

resource boundary.

LE25-210 Follow Up on South Trend

Drill holes LE26 -234, LE26 -236, and LE26 -245 were drilled to test for extensions to mineralization

intersected in LE25-210, located 480 metres east of the Deposit, which returned 0.486% U3O8 over 0.5 m

located three metres below the unconformity, within a 2.5 m interval averaging 0.115% U 3O8 extending

from 1.5 m above to 1.0 m below the unconformity.

LE26-234 returned the strongest result in this corridor, with a peak RS -125 reading over 0.5 m of 6,450

cps approximately 26 m above the unconformity within a broad zone of structural disruption, and a

second interval of 1,270 cps immediately above the unconformity contact in a fault gouge. The sandstone

column is moderately bleached from 157.6 m, becoming strongly bleached with pervasive interstitial

white clay from 200.0 m, with predominantly illitic clay alteration and minor kaolinite below 210.0 m. A

broad zone of structural disruption extends from 301.6 m to the unconformity, characterized by multiple

centimetre-scale clay gouges, quartz dissolution, broken and blocky core, and metre -scale zones of

unconsolidated core, with limonite staining intensifying in clay -rich intervals and sooty pyrite present in

more competent intervals. Semipelite and pelite w ere intersected in the basement below the

unconformity.

LE26-236 and LE26-245 intersected well-developed hydrothermal strongly bleached, illitic clay alteration

in the sandstone, and graphitic pelite in the basement, consistent with a prospective setting, however no

significant radioactivity was returned above background in either hole.

LE26-236 intersected a thick sequence of hydrothermally altered sandstone with predominantly illitic clay

alteration and lesser kaolinite from 120.0 m, becoming strongly bleached with pervasive interstitial white

clay from 242.0 m to the unconformity at 329.4 m. I ntermittent centimetre -scale zones of quartz

dissolution were intersected from 296.3 m to the unconformity, comprising less than 5% of the unit. Pelite

to graphitic pelite was intersected in the basement below the unconformity. No significant radioactivity

was returned above background.

LE26-245 intersected a thick sequence of hydrothermally altered sandstone, strongly bleached from 141.0

m, with predominantly illitic clay alteration and lesser kaolinite from 130.0 m to the unconformity. Two

zones of structural disruption were intersected: the fi rst from 217.1 to 253.7 m, characterized by

increased desilicification on fracture and fault surfaces with limonite staining; and the second

commencing at 272.4 m and extending to the unconformity at 324.5 m, characterized by clay gouge -

dominated faults, limonite-stained fractures, and pervasive interstitial white clay throughout. Limonite

staining intensifies from 320.1 m to the unconformity. Graphitic pelite was intersected in the basement

below the unconformity, with bleaching extending 2.0 m bel ow the unconformity contact and a 20 cm

zone of hydrothermal hematite at the base of the bleached basement zone. No significant radioactivity

was returned above background.

The winter drilling results, combined with the previously reported mineralization in LE25 -210, highlight

the potential for uranium mineralization along this eastern extension of the South Trend and warrant

further drill testing.

North Trend

The North Trend is characterized by discontinuous faults in sandstone and basement, associated with a

northern graphitic pelite basement unit and anomalous uranium geochemistry up to 50 metres north of

the Hurricane deposit.

LE26-239 was completed on the North Trend as a cross-strike test between drill holes LE25-218 and LE20-

56 (Figure 1), both of which returned strongly anomalous uranium geochemistry. (see news release dated

December 3, 2025). LE26-239 intersected 2,747 cps over 1.0 m from 336.8 m to 337.8 m, within a 1.5 m

interval of >350 cps, three metres below the unconformity at 334.2 m. This interval included 0.5 m with

an average RS-125 value of 3,203 cps. The sandstone column has a mixed illite -dickite-kaolinite spectral

mineralogy signature with illite dominant from 310 m to the unconformity where a chlorite component is

also present. Minor faults with associated clay alteration and desilicification are abundant between 133.2

m and 170.5 m, and from 264.9 m to 343.8 m. A third interval of minor clay-coated faults is present in the

basement from 359.9 m to 363.9 m. Pelite and semi-pelite were intersected in the basement.