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IsoEnergy to Commence Winter Uranium Drilling Programs at Thorburn Lake and Radio

Exploration Programs

IsoEnergy to Commence Winter Uranium Drilling Programs at

Thorburn Lake and Radio

Vancouver, BC, January 10, 2017 – IsoEnergy Ltd. (“ IsoEnergy ” or the “ Company ”) ( TSXV:ISO ) is pleased to

report that all exploration permits are in hand and winter drill campaigns at each of its Thorburn Lak e and

Radio uranium projects in the eastern Athabasca Basin of Saskatchewan will commence in mid-January.

As reported on January 5, 2017, results of Phase 1 drilling at Thorburn Lake included the intersection of

uranium mineralization in drill hole TBN16-19, and elevated radioactivity at the unconformity in several

other drill holes. The highlight of Phase 1 drilli ng at Radio was the discovery of a large zone of basement

clay alteration with a tenor and scale that is typi cally found close to significant uranium mineraliza tion ,

including the nearby Roughrider uranium deposit.

Thorburn Lake, located 7 kilometres east of the Cig ar Lake uranium mine, is 100% owned. IsoEnergy has an

exclusive right to earn a 70% interest in the Radio property, which is located 2 kilometres east of th e

Roughrider uranium deposit.

Thorburn Lake Drill Program

IsoEnergy is planning a 10 hole (4,300 metre) Phase 2 winter drilling program to follow up on the 2016

results. The primary target will be the northeast strike extension of the mineralization, alteration and

structural zone defined during the first phase of drilling in 2016. Secondary targets include several resistivity

low anomalies observed in an 85 line-kilometer DC-resistivity geophysical survey completed in October 2016.

Radio Property Drill Program

At Radio, IsoEnergy is planning a 10 hole (4,100 me tre) Phase 2 winter drilling program to follow up o n the

2016 results. The primary target will be uranium mineralization associated with the large zone of basement

clay alteration identified in the first phase of drilling in 2016.

Craig Parry, President and CEO, commented: “Given t he success of our initial drilling in 2016 in delin eating

mineralization and alteration typically associated with and nearby to uranium deposits such as Rio Tin to’s

Roughrider we very much look forward to commencing the winter phase of our drill campaign in coming

days.”

Qualified Person Statement

The disclosure of a scientific or technical nature contained in this news release was prepared by Stev e

Blower, P.Geo., IsoEnergy’s Vice President, Explora tion, who is a Qualified Person (as defined in Nati onal

Instrument 43-101 – Standards of Disclosure for Mineral Projects ). Mr. Blower has verified the data disclosed.

For additional information regarding the Company’s Radio project and Thorburn Lake project, including its

quality assurance and quality control procedures, p lease see the technical report dated effective Augu st 19,

2016 and September 26, 2016, respectively, in each case, on the Company’s profile at www.sedar.com. Th is

news release refers to properties other than those in which the Company has an interest. Mineralizatio n on

those other properties is not necessarily indicative of mineralization on the Company’s properties.

About IsoEnergy

IsoEnergy Ltd. is a well-funded uranium exploration and development company with a portfolio of

prospective projects in the eastern Athabasca Basin in Saskatchewan, Canada. IsoEnergy is led by a Board and

Management team with a track record of success in u ranium exploration, development and operations. The

Company was founded and is supported by the team at its major shareholder NexGen Energy Ltd.

Craig Parry

President and Chief Executive Officer

IsoEnergy Ltd.

+1 778 379 3211

[email protected]

www.isoenergy.ca

Investor Relations

Kin Communications

+1 604 684 6730

[email protected]

www.isoenergy.ca

The TSXV has neither approved nor disapproved the c ontents of this press release. Neither the TSXV nor its

Regulation Services Provider (as that term is defin ed in the policies of the TSXV) accepts responsibil ity for the

adequacy or accuracy of this release.

Forward-Looking Information

This news release contains "forward-looking informa tion" within the meaning of applicable Canadian

securities legislation. “Forward-looking informati on” includes, but is not limited to, statements wit h respect

to the activities, events or developments that the Company expects or anticipates will or may occur in the

future, including, without limitation, planned expl oration activities. Generally, but not always, forw ard-

looking information and statements can be identifie d by the use of words such as “plans”, “expects”, “ is

expected”, “budget”, “scheduled”, “estimates”, “for ecasts”, “intends”, “anticipates”, or “believes” or the

negative connotation thereof or variations of such words and phrases or state that certain actions, ev ents or

results “may”, “could”, “would”, “might” or “will b e taken”, “occur” or “be achieved” or the negative

connotation thereof.

Such forward-looking information and statements are based on numerous assumptions, including among

others, that the results of planned exploration act ivities are as anticipated, the price of uranium, t he

anticipated cost of planned exploration activities, that general business and economic conditions will not

change in a material adverse manner, that financing will be available if and when needed and on reason able

terms, and that third party contractors, equipment and supplies and governmental and other approvals

required to conduct the Company’s planned exploration activities will be available on reasonable terms and in

a timely manner. Although the assumptions made by t he Company in providing forward-looking information

or making forward-looking statements are considered reasonable by management at the time, there can be

no assurance that such assumptions will prove to be accurate.

Forward-looking information and statements also inv olve known and unknown risks and uncertainties and

other factors, which may cause actual events or res ults in future periods to differ materially from an y

projections of future events or results expressed o r implied by such forward-looking information or

statements, including, among others: negative opera ting cash flow and dependence on third party financ ing,

uncertainty of additional financing, no known miner al reserves or resources, potential forfeiture of t he Radio

Option Agreement, the limited operating history of the Company, the influence of a large shareholder,

alternative sources of energy and uranium prices, a boriginal title and consultation issues, reliance o n key

management and other personnel, actual results of e xploration activities being different than anticipa ted,

changes in exploration programs based upon results, availability of third party contractors, availabil ity of

equipment and supplies, failure of equipment to ope rate as anticipated; accidents, effects of weather and

other natural phenomena and other risks associated with the mineral exploration industry, environmenta l

risks, changes in laws and regulations, community r elations and delays in obtaining governmental or ot her

approvals.

Although the Company has attempted to identify impo rtant factors that could cause actual results to di ffer

materially from those contained in the forward-look ing information or implied by forward-looking

information, there may be other factors that cause results not to be as anticipated, estimated or inte nded.

There can be no assurance that forward-looking info rmation and statements will prove to be accurate, a s

actual results and future events could differ mater ially from those anticipated, estimated or intended .

Accordingly, readers should not place undue relianc e on forward-looking statements or information. Th e

Company undertakes no obligation to update or reiss ue forward-looking information as a result of new

information or events except as required by applicable securities laws.