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IsoEnergy Responds to Market Activity

Listings & Exchange

IsoEnergy Responds to Market Activity

Vancouver, BC, November 6, 2017 – IsoEnergy Ltd. (“IsoEnergy” or the “Company”) (TSXV: ISO; OTCQX:

ISENF), at the request of IIROC, confirms that the Company is unaware of any material undisclosed change

in the Company's business, operations or capital that would account for the recent trading activity in its

common shares.

About IsoEnergy

IsoEnergy is a uranium exploration company with a portfolio of prospective projects in the eastern

Athabasca Basin in Saskatchewan, Canada and a historic inferred mineral resource estimate at the

Mountain Lake uranium deposit in Nunavut. IsoEnergy is led by a Board and m anagement team with a

track record of success in uranium exploration, development and operations. The Company was founded

and is supported by the team at its major shareholder, NexGen Energy Ltd.

Craig Parry

Chief Executive Officer

IsoEnergy Ltd.

+1 778 379 3211

[email protected]

www.isoenergy.ca

Investor Relations

Kin Communications

+1 604 684 6730

[email protected]

www.isoenergy.ca

Neither the TSX Venture Exchange nor its Regulations Services Provider (as that term is defined in the

policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this

release.

This news release shall not constitute an offer to sell or a solicitation of any offer to buy any securities,

nor shall there be any sale of any securities in any jurisdiction in which such offer, solicitation or sale

would be unlawful. The securities referenced herein have not been, nor will they be, registered under the

United States Securities Act of 1933, as amended (the “U.S. Securities Act”), and such securities may not

be offered or sold within the United States absent registration under the U.S. Securities Act or an

applicable exemption from the registration requirements thereunder.

Forward-Looking Information

The information contained herein contains “forward -looking statements” within the meaning of the

United States Private Securities Litigation Reform Act of 1995 and “forward-looking information” within

the meaning of applicable Canadian securities legislation. “Forward-looking information” includes, but is

not limited to, statements with respect to the activities, events or developments that the Company

expects or anticipates will or may occur in the future, including, without limitation, planned exploration

activities. Generally, but not always, forward- looking information and statements can be identified by

the use of words such as “plans”, “expects”, “is expected”, “budget”, “scheduled”, “estimates”,

“forecasts”, “intends”, “anticipates”, or “believes” or the negative connotation thereof or variations o f

such words and phrases or state that certain actions, events or results “may”, “could”, “would”, “might”

or “will be taken”, “occur” or “be achieved” or the negative connotation thereof.

Such forward-looking information and statements are based on numerous assumptions, including among

others, that the results of planned exploration activities are as anticipated, the price of uranium, the

anticipated cost of planned exploration activities, that general business and economic conditions will not

change in a material adverse manner, that financing will be available if and when needed and on

reasonable terms, that third party contractors, equipment and supplies and governmental and other

approvals required to conduct the Company’s planned exploration activities will be available on

reasonable terms and in a timely manner. Although the assumptions made by the Company in providing

forward-looking information or making forward- looking statements are considered reasonable by

management at the time, there can be no assurance that such assumptions will prove to be accurate.

Forward-looking information and statements also involve known and unknown risks and uncertainties

and other factors, which may cause actual events or results in future periods to differ materially from any

projections of future events or results expressed or implied by such forward- looking information or

statements, including, among others: negative operating cash flow and dependence on third party

financing, uncertainty of additional financing, no k nown mineral reserves or resources, the limited

operating history of the Company, the influence of a large shareholder, alternative sources of energy and

uranium prices, aboriginal title and consultation issues, reliance on key management and other

personnel, actual results of exploration activities being different than anticipated, changes in exploration

programs based upon results, availability of third party contractors, availability of equipment and

supplies, failure of equipment to operate as anticipated; accidents, effects of weather and other natural

phenomena and other risks associated with the mineral exploration industry, environmental risks,

changes in laws and regulations, community relations and delays in obtaining governmental or other

approvals.

Although the Company has attempted to identify important factors that could cause actual results to

differ materially from those contained in the forward-looking information or implied by forward-looking

information, there may be other factors that cause results not to be as anticipated, estimated or

intended. There can be no assurance that forward- looking information and statements will prove to be

accurate, as actual results and future events could differ materially from those anticipated, estimated or

intended. Accordingly, readers should not place undue reliance on forward- looking statements or

information. The Company undertakes no obligation to update or reissue forward- looking information

as a result of new information or events except as required by applicable securities laws