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IsoEnergy Intersects Strong Uranium Mineralization in Initial Summer Drill Holes at the Hurricane Zone

Drill Results

IsoEnergy Intersects Strong Uranium Mineralization in Initial Summer

Drill Holes at the Hurricane Zone

Vancouver, BC, September 3, 2020 – IsoEnergy Ltd. (“IsoEnergy” or the “Company”) (TSXV: ISO; OTCQX: ISENF) is

pleased to report new intersections of strong uranium mineralization in the initial drill holes of the summer campaign

at the Hurricane zone. The Hurricane zone is a recent discovery of high- grade uranium mineralization on the

Company’s 100% owned Larocque East property (the “ Property”) in the Eastern Athabasca Basin of Saskatchewan

(Figure 1).

Highlights:

• Drill hole LE20-54 intersected 9.0m of uranium mineralization (>500 CPS) from 329.5 to 338.5m, including

4.0m of very strong radioactivity (>30,000 CPS) and 0.5m of off-scale radioactivity (>65,000 CPS)

• Drill hole LE20 -57 intersected 10.0m of uranium mineralization from (>500CPS) from 343.8 to 353.8m,

including 2.5m of very strong radioactivity (>40,000 CPS), and 0.5m of off-scale radioactivity (>65,000 CPS)

Note: Radioactivity is total gamma from drill core measured with an RS-125 hand-held spectrometer (RS-125).

Craig Parry, Chief Executive Officer commented: “The major disruptions to primary uranium supply over the last few

years, including the recent COVID related mine shutdowns, should continue to affect the uranium price positively in

the near -term. This is a terrific time to be reporting strong uranium drilling results, which the Hurricane zone

continues to deliver.”

Steve Blower, Vice President of Exploration commented: “Our summer drilling program is off to a great start. Based

on scintillometer counts, the first two drill holes from Drill 1 (LE20-54 and 57) are strongly mineralized and will extend

the zone of higher -grade uranium mineralization identified in our winter 2020 program . Our Technical team

continues to do a terrific job of targeting our drill holes based on the interpreted geology at the Hurricane zone.”

LE20-54 (Drill 1)

Drilled to expand the very strong mineralization intersected in drill hole LE20 -32A (8.5m @ 19.6% U3O8) during the

winter 2020 drill program, drill hole LE20-54 intersected the sub-Athabasca unconformity target approximately 7.0m

north of drill hole LE20 -32A (Figures 2 and 3). LE20 -54 cored strongly altered Athabasca sandstone before

successfully intersecting 9.0m of uranium mineralization that averages greater than 20,000 CPS (RS-125) from 329.5-

338.5m. Included in this interval is 4.0m of very strongly radioactive mineralization greater than 30,000 CPS (RS-

125). The mineralization is located at the sub-Athabasca unconformity, which was intersected at approximately

337.0m. A core photo showing the mineralized interval is provided in Figure 4.

LE20-57 (Drill 1)

Drilled to expand the very strong mineralization intersected in drill hole LE20 -52 (7.5m @ 22.7% U 3O8) during the

winter 2020 drill program, drill hole LE20-57 intersected the sub-Athabasca unconformity target approximately 5.0m

south of drill hole LE20-52 (Figures 2 and 5). Drill hole LE20-57 cored strongly altered Athabasca sandstone before

intersecting 10.0m of uranium mineralization that averages greater than 15,000 CPS (RS -125) from 343.8-353.8m.

Included in this interval is 2.5m of very strongly radioactive mineralization greater than 40,000 CPS (RS- 125). The

mineralization is located at the sub -Athabasca unconformity, which was intersected at approximately 349.0m. A

core photo showing the mineralized interval is provided in Figure 6.

LE20-55 (Drill 2)

Drill hole LE20-55 was drilled within the 250m along-strike gap on the eastern side of the Hurricane zone (Figure 2).

It was designed as an undercutting angled hole drilled purposefully beneath the Hurricane zone to locate the key

faults that control mineralization at Hurricane. The drill hole was a success, intersecting all of the important

structures, which can now be readily targeted with subsequent drill holes.

LE20-56 (Drill 2)

Similar to drill hole LE20-55, drill hole LE20-56 (Figures 2 and 7) was also drilled as an undercutting angled hole aimed

purposefully beneath the Hurricane zone to locate the important faults and graphitic units that control

mineralization at Hurricane. The drill hole successfully intersected several prominent faults and graphitic units and

was also weakly mineralized over a thick interval. LE20 -56 intersected 7.5m of weak uranium mineralization

(>500CPS RS-125) from 351.0-358.5m at the sub-Athabasca unconformity (Figure 7).

Next Steps

Drill 1 will remain on the west end of the Hurricane zone, continuing to evaluate the potential to expand the zone

of very strong uranium mineralization to the north and south on several of the westernmost cross -sections. Drill 2

will continue to evaluate targets both on the east side of the Hurricane zone, and on the west side. Samples collected

from the drilling completed to date have been shipped to the analytical laboratory. Chemical assay results are

expected within three to four weeks.

The Larocque East Property and the Hurricane Zone

The 100% owned Larocque East p roperty consists of 31 mineral claims totaling 15,878ha that are not encumbered

by any royalties or other interests. Larocque East is immediately adjacent to the north end of IsoEnergy’s Geiger

property and is 35km northwest of Orano Canada’s McClean Lake uranium mine and mill.

Along with other target areas, the Property covers a 15 -kilometre-long northeast extension of the Larocque Lake

conductor system; a trend of graphitic metasedimentary basement rocks that is associated with significant uranium

mineralization at the Hurricane zone, and in several occurrences on Cameco Corp . and Orano Canada Inc.’s

neighbouring property to the southwest of Larocque East. The Hurricane zone was discovered in July 2018 and was

followed up with 29 drill holes in 2019 and an additional 14 drill holes to date in 2020 . Dimensions are currently

575m along-strike, 40m wide, and up to 11m thick. The zone is open for expansion along- strike to the east and on

most sections. Mineralization is polymetallic and commonly straddles the sub-Athabasca unconformity 320 m below

surface. The best intersection to date is 33.9% U 3O8 over 8.5m in drill hole LE20 -34. Drilling at Cameco Corp.’s

Larocque Lake zone on the neighbo uring property to the southwest has returned historical intersections of up to

29.9% U3O8 over 7.0m in drill hole Q22 -040. Like the nearby Geiger property, Larocque East is located adjacent to

the Wollaston -Mudjatik transition zone - a major crustal sutur e related to most of the uranium deposits in the

eastern Athabasca Basin. Importantly, the sandstone cover on the Property is thin, ranging between 140m and 330m

in previous drilling.

Figure 1 – Larocque East Property Map

Figure 2 – Hurricane Zone Drill Hole Location Map

Figure 3 – Vertical Cross-Section 4510E (Drill Hole LE20-54)

Figure 4 – Core Photo of Mineralization in Drill Hole LE20-54

Figure 5 – Vertical Cross-Section 4435E (Drill Hole LE20-57)

Figure 6 – Core Photo of Mineralization in Drill Hole LE20-57