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IsoEnergy Intersects 7.5m of 22.7% U3O8 in Drill Hole LE20-52 Including 2.5m of 67.2% U3O8

Drill Results

IsoEnergy Intersects 7.5m of 22.7% U3O8 in Drill Hole LE20-52

Including 2.5m of 67.2% U3O8

Company to Host Conference Call Wednesday April 15, 2020 at 11:00am PST

Vancouver, BC, April 15, 2020 – IsoEnergy Ltd. (“IsoEnergy” or the “Company”) (TSXV: ISO; OTCQX: ISENF) is pleased

to report final assay results from the winter 2020 drilling program at the Hurricane zone. Discovered in 2018 at the

Larocque East property, the Hurricane zone is a recent discovery of high-grade uranium mineralization. Larocque

East is 100% owned by IsoEnergy and is located in the prolific Eastern Athabasca Basin of Saskatchewan (Figure 1).

Winter Drilling Selected Highlights:

 Drill hole LE20-52 assays average 22.7% U 3O8 over 7.5m from 318.5 to 326.0m, including 67.2% U 3O8 over

2.5m from 322.5 to 325.0m

 Drill hole LE20-53 assays average 11.7% U3O8 over 10.5m from 317.5 to 328.0m, including 40.4% U 3O8 over

3.0m from 324.5 to 327.5m

 Drill Hole LE20-51 assays average 14.5% U 3O8 and 3.5% Ni over 7.5m from 322.5 to 330.0m*

 Drill Hole LE20-40 assays average 20.5% U 3O8 over 4.0m from 322.5 to 326.5m*

 Drill Hole LE20-34 assays average 33.9% U 3O8 over 8.5m from 326.0 to 334.5m, including 5.0m averaging

57.1% U3O8 from 328.0 to 333.0m*

 Drill Hole LE20-32A assays average 19.6% U 3O8 over 8.5m from 329.5 to 338.0m, including 2.5m of 63.6%

U3O8 from 334.5 to 337.0m*

*Previously released assay results

Craig Parry, Chief Executive Officer commented: “I’d like to congratulate our technical team on these latest results

and on the highly successful winter drilling program. Drilling has continued to deliver long intervals of high-grade

pitchblende uranium mineralization, confirming Hurricane as major discovery. It is worth noting that the Hurricane

deposit is in an exceptional location in the eastern Athabasca close to key infrastructure and only 40km from Orano’s

McLean Lake Mill. These latest results from our winter program come at a crucial time for the uranium exploration

and mining sector. In recent days we have seen the major producers announce extended closures of their mines and

mills which we estimate has reduced global uranium production volumes by over 50%. Already we have seen the

uranium spot price rise over 30% from $24/lb three weeks ago to $31.50/lb today, breaking the important

psychological barrier of $30/lb in the process. This rise has occurred without the full impact of physical product being

removed from the market and when these announced supply cuts take full effect in coming weeks, we expect to see

further upward pressure on prices. Against this backdrop IsoEnergy remains well positioned with $3.5m in cash and

we look forward to reporting on plans for further drilling at our high-grade Hurricane discovery.”

Steve Blower, Vice President of Exploration commented: “The last two drill holes of the campaign have returned

very high-grade uranium assays over long intervals. The southernmost drill holes on all five sections in the western

end of the Hurricane zone are now all strongly mineralized. Clearly there is room for expansion of this very high-

grade area within the larger Hurricane zone footprint, which now measures 575m long, up to 40m wide and up to

11m thick.”

Investor Conference Call and Webcast

The Company will be hosting a conference call today, April 15, 2020 at 11:00 AM PST (2:00 PM EST), to give a

corporate presentation, discuss the winter drilling program, and host a Q&A for investors and other interested

parties.

Details of the Call:

Participant toll free dial in number: (844) 618-5255

Audience URL:

https://onlinexperiences.com/Launch/QReg/ShowUUID=3DFB8AE5-B96E-4255-AE54-C68AD316766F

The presentation to be covered on the call can also be found on the Company’s website:

https://www.isoenergy.ca/

Final Assays Received

Drill Hole LE20-52 (Hurricane Section 4435E)

Drill hole LE20-52 was designed to evaluate the potential for additional high-grade mineralization to the south of

drill holes LE20-40 and LE20-34 (Figures 2 and 3). It successfully intersected a thick interval of strong uranium

mineralization at the sub-Athabasca unconformity that averages 22.7% U 3O8 over 7.5m from 318.5 to 326.0m. The

interval includes a very high-grade section that averages 67.2% U 3O8 over 2.5m from 322.5 to 325.0m. Within the

very high-grade section is a subinterval of continuous off-scale (>65K CPS on an RS-125 handheld spectrometer)

mineralization that averages 79.9% U3O8 over 1.5m from 322.5 to 324.0m. Figure 4 is a core photo of the mineralized

interval.

Drill Hole LE20-53 (Hurricane Section 4410E)

Drill hole LE20-53 was completed 25m along-strike to the west of drill hole LE20-52 (Figures 2 and 5). It successfully

intersected 10.5m of strong uranium mineralization at the sub-Athabasca unconformity from 317.5 to 328.0m that

averages 11.7% U 3O8 (Figures 2 and 4). The intersection includes a 3.0m subinterval of very strong uranium

mineralization that averages 40.4% U 3O8 from 324.5 to 327.5m. Within the very high-grade section is a subinterval

of off-scale (>65K CPS on an RS-125 handheld spectrometer) mineralization that averages 62.7% U 3O8 over 0.5m

from 326.0 to 326.5m. Figure 6 is a core photo of the mineralized interval.

Next Steps

All assays from the 2020 winter drilling program at the Hurricane zone have now been received. Data compilation

and interpretation of the drilling results are well underway, as is planning for a summer drilling program that will

continue to define the extent of the Hurricane zone. The timing and amount of summer drilling may be impacted

by the COVID-19 pandemic. The Company continues to monitor the situation will make decisions regarding future

work programs in due course.

The Larocque East Property and the Hurricane Zone

The 100% owned Larocque East property consists of 20 mineral claims totaling 8,371 ha that are not encumbered

by any royalties or other interests. Larocque East is immediately adjacent to the north end of IsoEnergy’s Geiger

property and is 35 km northwest of Orano Canada’s McClean Lake uranium mine and mill.

Along with other target areas, the Property covers a 15-kilometre-long northeast extension of the Larocque Lake

conductor system; a trend of graphitic metasedimentary basement rocks that is associated with significant uranium

mineralization at the Hurricane zone, and in several occurrences on Cameco Corp. and Orano Canada Inc.’s

neighbouring property to the southwest of Larocque East. The Hurricane zone was discovered in July 2018 and was

followed up with 29 drill holes in 2019 and an additional 14 drill holes to date in 2020. Dimensions are currently

575m along-strike, 40m wide and up to 11m thick. The zone is open for expansion along-strike to the east and on

most sections. Mineralization is polymetallic and commonly straddles the sub-Athabasca unconformity 320 m below

surface. The best intersection to date is 33.9% U 3O8 over 8.5m in drill hole LE20-34. Drilling at Cameco Corp.’s

Larocque Lake zone on the neighbouring property to the southwest has returned historical intersections of up to

29.9% U3O8 over 7.0m in drill hole Q22-040. Like the nearby Geiger property, Larocque East is located adjacent to

the Wollaston-Mudjatik transition zone - a major crustal suture related to most of the uranium deposits in the

eastern Athabasca Basin. Importantly, the sandstone cover on the Property is thin, ranging between 140m and 330m

in previous drilling.

Table 1 – 2020 Hurricane Zone Results

Hole-ID From (m) To (m) Length (m) Radioactivity 1,2 Chemical Assays Orientation Location

(CPS) U 3O8 (%) Ni (%) (Azm/Dip)

LE20-303 330.0 335.5 5.5 >500 7.1 0.9 180/-80 Section 4460E

incl. 331.0 331.5 0.5 >10,000 3.4 0.1

and incl. 332.0 333.5 1.5 >20,000 24.0 2.7

LE20-32A3 329.5 338.0 8.5 >500 19.6 1.1 180/-80 Section 4510E

incl. 334.5 337.0 2.5 >20,000 63.6 0.4

incl. 335.0 336.5 1.5 Off-scale 5 76.7 0.3

LE20-343 326.0 334.5 8.5 >500 33.9 0.5 180/-80 Section 4435E

incl. 328.0 333.0 5.0 >20,000 57.1 0.7

incl. 329.5 331.5 2.0 Off-scale 5 62.8 0.4

LE20-363 332.5 333.5 1.0 >500 3.7 1.0 180/-80 Section 4460E

incl. 332.5 333.0 0.5 >20,000 5.5 1.3

LE20-383 319.5 327.0 7.5 >500 2.0 0.2 000/-90 Section 4460E

incl. 325.0 325.5 0.5 >20,000 3.5 0.0

and incl. 326.0 326.5 0.5 >20,000 9.8 0.1

LE20-403 319.5 320.5 1.0 >500 0.1 0.1 000/-90 Section 4435E

and 322.5 326.5 4.0 >500 20.5 1.0

incl. 323.0 324.5 1.5 >20,000 53.8 2.3

incl. 323.0 323.5 0.5 Off-scale 5 64.9 0.2

LE20-423 326.0 329.0 3.0 >500 0.4 0.2 000/-90 Section 4410E

LE20-443 325.5 326.0 0.5 >500 0.2 0.0 000/-90 Section 4460E

and 327.5 329.0 1.5 >500 0.3 0.6

LE20-463 318.0 328.0 10.0 >500 3.6 1.4 000/-90 Section 4485E

incl. 323.0 325.0 2.0 >20,000 12.8 1.6

and 326.0 327.0 1.0 >10,000 4.5 4.9

LE20-483 316.0 327.5 11.5 >500 1.3 0.3 000/-90 Section 4485E

incl. 321.0 321.5 0.5 >10,000 3.6 1.2

and incl. 324.0 327.0 3.0 >10,000 3.3 0.2

incl. 324.5 325.0 0.5 >20,000 5.1 0.2

LE20-493 320.5 329.5 9.0 >500 1.1 0.1 000/-90 Section 4510E

incl. 326.5 327.5 1.0 >10,000 3.4 0.0

LE20-513 322.5 330.0 7.5 >500 14.5 3.5 000/-90 Section 4510E

incl. 325.5 329.0 3.5 >10,000 30.9 7.1

Incl. 326.0 329.0 3.0 >20,000 35.2 8.2

LE20-524 318.5 326.0 7.5 >500 22.7 0.4 000/-90 Section 4435E

incl. 322.5 325.0 2.5 >10,000 67.2 0.7

incl. 322.5 324.0 1.5 Off-scale 5 79.9 0.5

LE20-534 317.5 328.0 10.5 >500 11.7 0.3 000/-90 Section 4410E

incl. 324.5 327.5 3.0 >20,000 40.4 0.8

incl. 326.0 326.5 0.5 Off-scale 5 62.7 0.3

Notes: 1. Radioactivity is total gamma from drill core measured with an RS-125 hand-held spectrometer

2. Measurements of total gamma on drill core are an indication of uranium content, but may not correlate with chemical assays

3. Radioactivity and chemical assays previously disclosed

4. Radioactivity previously disclosed

5. Off-scale radioactivity is defined as exceeding 65,536 cps, the maximum measurable by an RS-125 spectrometer

Figure 1 – Larocque East Property Map

Figure 2 – Western Hurricane Zone Drill Hole Location Map

Figure 3 – Cross Section 4435E (Drill Hole LE20-52)

Figure 4 – Drill Hole LE20-52 Core Photo of Mineralization

Figure 5 – Cross Section 4410E (Drill Hole LE20-53)