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IsoEnergy Announces Filing and Mailing of the Management Information Circular in Connection with its Special Meeting of Shareholders to Approve the Acquisition of Anfield

Shareholder Meetings

IsoEnergy Announces Filing and Mailing of the Management Information Circular in

Connection with its Special Meeting of Shareholders to

Approve the Acquisition of Anfield

• Your vote is important no matter how many votes you hold. Vote today.

• The Board of Directors of IsoEnergy recommends that Shareholders vote

IN FAVOUR of both Meeting Resolutions

• Shareholders who have questions or need assistance with voting their shares should contact

IsoEnergy’s proxy solicitation agent and shareholder communications advisor Laurel Hill Advisory

Group by telephone at 1-877-452-7184 or by email at [email protected].

Toronto, ON – November 6, 2024 – IsoEnergy Ltd. (“IsoEnergy”) (TSX: ISO; OTCQX: ISENF) is pleased announce

that its management information circular (the “Circular”) and related materials in connection with the special

meeting (th e “Meeting”) of shareholders (the “ IsoEnergy Shareholders ”) are now available on IsoEnergy’s

website at www.isoenergy.ca/investors/special-meeting/ as well as under IsoEnergy ’s profile on SEDAR+

(www.sedarplus.ca). IsoEnergy commenced the mailing of the Circular and related materials for the Meeting to

IsoEnergy Shareholders on Wednesday, November 6, 2024.

The Arrangement and Meeting Details

On October 1, 2024, IsoEnergy and Anfield Energy Inc. (“Anfield”) entered into a definitive agreement (the

“Arrangement Agreement”) pursuant to which IsoEnergy has agreed to acquire all of the issued and outstanding

common shares of Anfield (the “ Anfield Shares ”) by way of a court -approved plan of arrangement (the

“Arrangement”).

If the Arrangement is completed, Anfield will become a wholly -owned subsidiary of IsoEnergy. IsoEnergy

Shareholders will continue to own their existing common shares of IsoEnergy (“IsoEnergy Shares ”) on

completion of the Arrangement. Following the completion of the Arrangement, former IsoEnergy Shareholders

are expected to own approximately 83.8%, and former Anfield shareholders are expected to own approximately

16.2% of the issued and outstanding IsoEnergy Shares on a fully-diluted in-the-money basis, in each case based

on the number of securities of IsoEnergy and Anfield issued and outstanding as of October 1, 2024.

At the Meeting, IsoEnergy Shareholders will be asked to vote on an ordinary resolution approving the issuance

of IsoEnergy Share s in connection with the Arrangement (the “ Share Issuance Resolution”) and a special

resolution approving a potential consolidation of the IsoEnergy Shares (together with the Share Issuance

Resolution, the “Resolutions”), in each case as more particularly described in the Circular.

IsoEnergy will hold its Meeting on December 3 , 202 4, at 2:00 pm (Toronto time) online at

meetnow.global/M9YNP66 with the ability for IsoEnergy Shareholders to participate electronically as explained

further in the Circular.

IsoEnergy Board of Directors’ Recommendations

The Board of Directors of IsoEnergy unanimously recommends that IsoEnergy

shareholders vote FOR both Resolutions

IsoEnergy Shareholders are encouraged to read the Circular in detail and vote your IsoEnergy Shares as soon as

possible. The deadline for voting your IsoEnergy S hares is at 2:00 p.m. (Toronto time) on Friday, November 29,

2024.

Strategic Rationale for the Arrangement

The following is a summary of certain principal reasons for the unanimous determination of the IsoEnergy Board

that the Arrangement is in the best interests of IsoEnergy and the unanimous recommendation of the IsoEnergy

Board that IsoEnergy Shareholders vote FOR the Share Issuance Resolution:

• Expected Expansion of Near -Term U.S. Uranium Production Capacity – The combined portfolio

(the “Combined Portfolio”) of permitted past-producing mines and development projects in the

Western U.S. is expected to provide IsoEnergy with substantial increased uranium production

potential in the short, medium and long term.

• Ownership of Shootaring Canyon Mill – Completion of the Arrangement secures ownership of the

Shootaring Canyon Mill, one of only three permitted conventional uranium mills in the U.S., and

which is located adjacent to IsoEnergy’s Tony M Mine. A production reactivation plan has been

submitted to the UDEQ for the Shootaring Canyon Mill. The plan addresses the updating of the

mill's radioactive materials licence from its current standby status to operational status as well as

to increase throughpu t from 750 st pd to 1,000 stpd and expand licensed annual production

capacity from 1 million lbs U₃O₈ to 3 million lbs U₃O₈. IsoEnergy also has existing toll- milling

agreements in place with Energy Fuels for its White Mesa Mill to provide additional processing

flexibility for certain of IsoEnergy’s mines.

• Complimentary Project Portfolio Provides Immediate Operational Synergies – Benefits from the

proximity of the Combined Portfolio in Utah and Colorado are expected to include, reduced

transportation costs, increased operational flexibility for mining and processing, reduction in G&A

on a per pound basis, and risk diversification through multiple production sources.

• Aligned with Goal of Building a Multi-Asset Uranium Producer in Tier-One Jurisdictions – Beyond

the impressive Combined Portfolio in the U.S., the pro forma company will have a robust pipeline

of development and exploration -stage projects in tier -one uranium jurisdictions, including the

world’s highest grade published indicated uranium mineral resource in Canada’s Athabasca Basin.

• Well-Timed to Capitalize on Strong Momentum in the Nuclear Industry – Recent industry

headlines relating to increasing demand and support for nuclear power are expected to drive

uranium demand, and by extension, prices, coinciding with expected production and development

of the Combined Portfolio.

• Enhanced Capital Markets Profile with Strong Shareholder Base . The Arrangement is expected

to provide IsoEnergy with greater access to capital and trading liquidity, strengthened position for

future M&A, expanded research coverage and increased attractiveness among investors and

utilities. Additionally, the pro forma company will be backed by corporate and institutional

investors of both companies, including, NexGen Energy Ltd., Mega Uranium Ltd., enCore Energy

Corp., Energy Fuels Inc. and Uranium ETFs.

Additional details with respect to the reasons for the IsoEnergy Board’s recommendation are described in the

Circular, which IsoEnergy Shareholders are urged to read in its entirety.

How To Vote

Registered Shareholders Beneficial Shareholders

Common Shares held in own name and

represented by a physical certificate or DRS.

Common Shares held with a broker, bank or

other intermediary.

Internet www.investorvote.com www.proxyvote.com

Telephone 1-866-732-8683 Call the applicable number listed on the voting

instruction form.

Mail Return the form of proxy in the enclosed

envelope.

Return the voting instruction form in the

enclosed envelope.

Shareholder Questions

IsoEnergy Shareholders who have any questions or require assistance with voting may contact Laurel Hill

Advisory Group, IsoEnergy’s proxy solicitation agent and shareholder communications advisor:

Laurel Hill Advisory Group

Toll Free: 1-877-452-7184 (for shareholders in North America)

International: +1 416-304-0211 (for shareholders outside Canada and the US)

By Email: [email protected]

About IsoEnergy Ltd.

IsoEnergy Ltd. (TSX: ISO) (OTCQX: ISENF) is a leading, globally diversified uranium company with substantial

current and historical mineral resources in top uranium mining jurisdictions of Canada, the U.S., and Australia at

varying stages of development, p roviding near, medium, and long- term leverage to rising uranium prices.

IsoEnergy is currently advancing its Larocque East Project in Canada’s Athabasca Basin, which is home to the

Hurricane deposit, boasting the world’s highest grade Indicated uranium Mineral Resource.

IsoEnergy also holds a portfolio of permitted, past-producing conventional uranium and vanadium mines in Utah

with a toll milling arrangement in place with Energy Fuels Inc. These mines are currently on stand -by, ready for

rapid restart as market conditions permit, positioning IsoEnergy as a near-term uranium producer.

For More Information, Please Contact:

Philip Williams

CEO and Director

[email protected]

1-833-572-2333

X: @IsoEnergyLtd

www.isoenergy.ca

Neither the TSXV nor its Regulation Services Provider (as that term is defined in the policies of the TSXV) accepts

responsibility for the adequacy or accuracy of this news release. No securities regulatory authority has either

approved or disapproved of the contents of this news release.

None of the securities to be issued pursuant to the Arrangement have been or will be registered under the United

States Securities Act of 1933, as amended (the “U.S. Securities Act”), or any state securities laws, and any

securities issuable in the Arrange ment are anticipated to be issued in reliance upon available exemptions from

such registration requirements pursuant to Section 3(a)(10) of the U.S. Securities Act and applicable exemptions

under state securities laws. This press release does not constitute an offer to sell, or the solicitation of an offer to

buy, any securities.

Cautionary Statement Regarding Forward-Looking Information

This press release contains “forward-looking information” within the meaning of applicable Canadian securities

legislation. Generally, forward-looking information can be identified by the use of forward- looking terminology

such as “plans”, “expects” or “does not expect”, “is expected”, “budget”, “scheduled”, “estimates”, “forecasts”,

“intends”, “anticipates” or “does not anticipate”, or “believes”, or variations of such words and phrases or state

that certain actions, events or results “may”, “could”, “woul d”, “might” or “will be taken”, “occur” or “be

achieved”. These forward -looking statements or information may relate to the Arrangement , including

statements with respect to the consummation of the Arrangement ; receipt and timing of approval of the

IsoEnergy Shareholders with respect to the Arrangement ; the anticipated benefits of the Arrangement to

IsoEnergy and its shareholders; the anticipated mailing of the Circular and the date of the Meeting; the expected

ownership interest of IsoEnergy Shareholders and Anfield shareholders in the combined company; anticipated

strategic and growth opportunities for the combined company; the successful integration of the businesses of

IsoEnergy and Anfield; the potential for, success of and anticipated timi ng of commencement of future

commercial production at the companies’ properties, including expectations with respect to any permitting,

development or other work that may be required to bring any of the project s into development or production;

increased demand for nuclear power and uranium and the expected impact on the price of uranium; and any

other activities, events or developments that the companies expect or anticipate will or may occur in the future.

Forward-looking statements are necessarily based upon a number of assumptions that, while considered

reasonable by management at the time, are inherently subject to business, market and economic risks,

uncertainties and contingencies that may cause actual results, performance or achievements to be materially

different from those expressed or implied by forward-looking statements. Such assumptions include, but are not

limited to, assumptions that IsoEnergy and Anfield will complete the Arrangemen t in accordance with, and on

the timeline contemplated by the terms and conditions of the relevant agreements; that the parties will receive

the required shareholder, regulatory, court and stock exchange approvals and will satisfy, in a timely manner,

the other conditions to the closing of the Arrangement; the accuracy of management’s assessment of the effects

of the successful completion of the Arrangement and that the anticipated benefits of the Arrangement will be

realized; the anticipated mineralization of IsoEnergy’s and Anfield’s projects being consistent with expectations

and the potential benefits from such projects and any upside from s uch projects; the price of uranium; that

general business and economic conditions will not change in a materially adverse manner; that financing will be

available if and when needed and on reasonable terms; and that third party contractors, equipment and supplies

and governmental and other approvals required to conduct the combined company’s planned activities will be

available on reasonable terms and in a timely manner. Although IsoEnergy has attempted to identify important

factors that could cause actual results to differ materially from those contained in forward-looking information,

there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no

assurance that such information will prove to be accurate, as actual results and future events could differ

materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on

forward-looking information.

Such statements represent the current views of IsoEnergy with respect to future events and are necessarily based

upon a number of assumptions and estimates that, while considered reasonable by IsoEnergy, are inherently

subject to significant business, economic, competitive, political and social risks, contingencies and uncertainties.

Risks and uncertainties include, but are not limited to the following: the inability of IsoEnergy and Anfield to

complete the Arrangement; a material adverse change in the timing of and the terms and conditions upon which

the Arrangemen tis completed; the inability to satisfy or waive all conditions to closing the Arrangement ; the

failure to obtain shareholder, regulatory, court or stock exchange approvals in connection with the Arrangement;

the inability of the combined company to realize the benefits anticipated from the Arrangemen t and the timing

to realize such benefits; the inability of the consolidated entity to realize the benefits anticipated from the

Arrangement and the timing to realize such benefits, including the exploration and drilling targets described

herein; unanticipated changes in market price for IoOEnergy Shares and/or Anfield shares; changes to IsoEnergy’s

and/or Anfield’s current and future business plans and the strategic alternatives available thereto; growth

prospects and outlook of Anfield’s business; regulatory determinations and delays; stock market conditions

generally; demand, supply and pricing for uranium; and general economic and political conditions in Canada, the

United States and other jurisdictions where the applicable party conducts business. Other factors which could

materially affect such forward- looking information are described in the risk factors in IsoEnergy’s most recent

annual information form, the Circular and IsoEnergy’s other filings with the Canadian securities regulators which

are available, respectively, on each company’s profile on SEDAR+ at www.sedarplus.ca. IsoEnergy do es not

undertake to update any forward-looking information, except in accordance with applicable securities laws.