PlantEXT and Israel’s Agricultural Research Organization Report Progress on Research and Development of Medical Cannabis Formulations for Inflammatory Bowel Disease
PlantEXT and Israel’s Agricultural Research Organization Report Progress on Research
and Development of Medical Cannabis Formulations for Inflammatory Bowel Disease
FOR IMMEDIATE RELEASE
Toronto, Ontario—April 11, 2019 - PlantEXT Ltd. (" PlantEXT") and BB1 Acquisition Corp.
(TSXV:BBA.P) (“BB1”) are pleased to announce that following more than three years of dedicated
research in the laboratory of Prof. Hinanit Koltai, Agricultural Research Organization (“ARO ”),
PlantEXT and the State of Israel’s ARO, have successfully refined earlier discoveries to develop
active, anti-inflammatory formulations of cannabinoids and terpenes derived from cannabis . In
vitro testing on human cell lines and ex vivo testing on inflamed colon biopsies of patients with
inflammatory bowel disease (“IBD”) has allowed us to identify, at the molecular level, synergistic
combinations of cannabinoids and terpenes to help reduce inflammation and to potentially improve
the quality of life for IBD patients.
PlantEXT has entered into a license agreement with The Government of the State of Israel and has
funded research at ARO over the past 3 years, and acquired the exclusive global rights to
commercialize ARO’s intellectual property (“IP”) and products for the treatment of IBD.
Doug Sommerville, CEO of PlantEXT stated, “PlantEXT and ARO are working together to
develop a first-generation medical cannabis treatment that targets inflammation related to IBD. We
are excited to report that o ur world class team, utilizing our proprietary testing methodology, has
identified the most active anti- inflammatory formulations for IBD in our program to date . These
formulations have shown significantly greater anti -inflammatory activity than certain traditional
steroid therapies currently used in the treatment of IBD. We are finalizing arrangements for Good
Manufacturing Practice (GMP) manufacturing, compliant packaging and pharmacy distribution in
Israel and other markets and are on track to launch our first product commercially, in the current
quarter”.
Ex vivo studies are being conducted on fresh human biopsies of inflamed colon tissue from IBD
patients, to measure the anti-inflammatory activity of various formulations utilizing ARO’s patent-
pending methodology that has been licensed to PlantEXT . Studies at ARO have been supervised
by Professor Hinanit Koltai, a leading author of more than 80 peer-reviewed publications and 30
book chapters and invited reviews and a full professor -grade Senior Research Scientist at ARO’s
Volcani Centre.
ARO and PlantEXT’s in vitro studies on human cell lines and e x vivo studies on biopsies have
created a growing library of measured anti -inflammatory activity from a variety of fractions and
synergistic combinations of cannabinoids and terpenes from cannabis . ARO and PlantEXT’s
patent-pending methodologies support a proprietary research platform that facilitates the
development of anti -inflammatory formulations and has potential applications in facilitating
personalized treatments.
About PlantEXT
PlantEXT is an Israeli company focused on developing and commercializing the world's most
effective medical cannabis formulations for the treatment of inflammation related medical
conditions. Plant EXT has entered into a strategic partnership with the State of Isra el's ARO to
develop and commercialize a treatment for IBD. PlantEXT also operates independent research and
development facilities near Tel Aviv, where it is developing a pipeline of anti -inflammatory
products supported by pre -clinical and clinical research. PlantEXT is preparing to begin
commercial marketing of ARO’s IBD product in Israel during Q 2 2019, and intends to launc h
additional products and to expand internationally, later in 2019.
PlantEXT and BB1 have entered into a letter of intent for a Qualifying Transaction that is intended
to lead to Plant EXT becoming a public company through a reverse take -over of BB1 (the
“Proposed Transaction”).
About BB1
BB1 is a capital pool company whose sole business is the identification and evaluation of assets or
businesses with a view to completing a qualifying transaction.
For more information please contact Doug Sommerville, PlantEXT’s CEO at +1 416 640 5353.
For more information about BB1 please contact Stephen Shefsky, BB1’s CEO at +1 416 366 4200.
Forward Looking Information, Disclaimer and Reader Advisory
The information in this news release includes certain information and statements about
management's view of future events, expectations, plans and prospects that constitute forward
looking statements. The foregoing statements are based upon assumptions tha t are subject to
significant risks and uncertainties. Because of these risks and uncertainties and as a result of a
variety of factors, the actual results, expectations, achievements or performance may differ
materially from those anticipated and indicated by these forward -looking statements. Forward-
looking statements in this news release include, but are not limited to, the ability of the Company
to complete the Transaction. Any number of factors could cause actual results to differ materially
from these forward-looking statements as well as future results. Although the Company believes
that the expectations reflected in forward looking statements are reasonable, it can give no
assurance that the expectations of any forward-looking statements will prove to be correct. Except
as required by law, the Company disclaims any intention and assumes no obligation to update or
revise any forward -looking statements to reflect actual results, whether as a result of new
information, future events, changes in assumptions, changes in factors affecting such forward -
looking statements or otherwise. No assurance can be given as to the timing, approval or ultimate
terms of any export license granted to PlantEXT by the government of Israel. Neither the TSX
Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of
the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.
All information provided in this press release relating to PlantEXT has been provi ded by
management of PlantEXT and not independently verified by management of BB1. As of the date
of this press release, BB1 has not entered into a definitive agreement with PlantEXT and readers
are cautioned that there can be no assurances that such an agreement will be executed or the
Proposed Transaction completed.
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