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IsoEnergy Acquires Additional Securities in Premier American Uranium Inc.

Mergers & Acquisitions

IsoEnergy Acquires Additional Securities in Premier American Uranium Inc.

Toronto, ON, December 30, 2025 – IsoEnergy Ltd. (“IsoEnergy”, or the “Company”) (NYSE American: ISOU;

TSX: ISO) is pleased to announce that it has acquired (the “Transaction”) 2,135,760 common shares (the “PUR

Common Shares”) of Premier American Uranium Inc. (“PUR”) and warrants to acquire an additional 2,708,627

PUR Shares in consideration for the issuance of an aggregate of 100,000 common shares of the Company (the

“ISO Shares”). The ISO Shares were issued at a deemed price of $11.58 per share, representing aggregate

consideration of $1,158,000.

Philip Williams, CEO and Director of IsoEnergy, commented, “As a co-founder of PUR in late 2023, we have

been impressed by the company’s consistent track record of value creation through disciplined M&A and asset

advancement. Against a strengthening uranium price environment and powerful tailwinds in the nuclear

sector—particularly in the United States, where PUR is focused —we believe this is an opportune time to

increase our equity exposure to the company.”

Immediately prior to the completion of the Transaction, the Company owned an aggregate of 4,245,841 PUR

Common Shares and warrants to acquire 167,708 PUR Common Shares, representing approximately 6.27% of

the outstanding PUR Common Shares on a non-diluted basis and approximately 6.50% of the outstanding PUR

Common Shares on a partially -diluted basis assuming exercise of all of the warrants held by the Company

(before giving effect to the conversion of the c ompressed shares of PUR (the “ Compressed Shares ”)).

Assuming the conversion of all of the issued and outst anding Compressed Shares into PUR Common Shares,

the PUR Common Shares and warrants held by the Company represented approximately 5.38% of the PUR

Common Shares on a non-diluted basis and approximately 5.58% of the outstanding PUR Common Shares on

partially-diluted basis assuming exercise of the warrants held by the Company.

Following completion of the Transaction, the Company owns an aggregate of 6,381,601 PUR Common Shares

and warrants to acquire an aggregate of 2,876,335 PUR Common Shares, representing approximately 9.42%

of the outstanding PUR Common Shares on a non-diluted basis and approximately 13.11% of the outstanding

PUR Common Shares on a partially-diluted basis assuming exercise of all of the warrants held by the Company

(before giving effect to the conversion of the Compressed Shares). Assuming the conversion of all of the issued

and outstanding Compressed Shares into PUR Common Shares, the PUR Common Shares and warrants held

by the Company represent approximately 8.09% of the PUR Common Shares on a non -diluted basis and

approximately 11.32% of the outstanding PUR Common Shares on partially-diluted basis assuming exercise of

the warrants held by the Company.

The securities of PUR held by IsoEnergy are held for investment purposes. Although IsoEnergy has no current

plans with respect to the securities, depending on market conditions, general economic and industry

conditions, trading prices of PUR’s securities, PUR’s business, financial condition and prospects and/or other

relevant factors, IsoEnergy may develop such plans or intentions in the future and, at such time, may from

time to time acquire additional securities, dispose of some or all of the existing or additional securities or may

continue to hold securities of PUR.

This news release is issued pursuant to National Instrument 62-103 – The Early Warning System and Related

Take-Over Bid and Insider Reporting Issues , which also requires an early warning report to be filed with the

applicable securities regulators containing additional information with respect to the foregoing matters. A

copy of the early warning report of IsoEnergy will be available under PUR’s profile on SEDAR+ at

www.sedarplus.ca. IsoEnergy’s registered office is located at 217 Queen Street West, Toronto, ON M5V 0R2.

About IsoEnergy Ltd.

IsoEnergy (NYSE American: ISOU; TSX: ISO) is a leading, globally diversified uranium company with substantial

current and historical mineral resources in top uranium mining jurisdictions of Canada, the U.S. and Australia

at varying stages of development, providing near-, medium- and long-term leverage to rising uranium prices.

IsoEnergy is currently advancing its Larocque East project in Canada’s Athabasca basin, which is home to the

Hurricane deposit, boasting the world’s highest-grade indicated uranium mineral resource.

IsoEnergy also holds a portfolio of permitted past -producing, conventional uranium and vanadium mines in

Utah with a toll milling arrangement in place with Energy Fuels. These mines are currently on standby, ready

for rapid restart as market conditions permit, positioning IsoEnergy as a near-term uranium producer.

For More Information, Please Contact:

Philip Williams

CEO and Director

[email protected]

1-833-572-2333

X: @IsoEnergyLtd

www.isoenergy.ca

Cautionary Statement Regarding Forward-Looking Information

This press release contains forward-looking statements” within the meaning of the United States Private

Securities Litigation Reform Act of 1995 and “forward-looking information” within the meaning of applicable

Canadian securities legislation (collectively, referred to as “forward-looking information”). Generally, forward-

looking information can be identified by the use of forward-looking terminology such as “plans”, “expects” or

“does not expect”, “is expected”, “budget”, “scheduled”, “estimates”, “forecasts”, “intends”, “anticipates” or

“does not anti cipate”, or “believes”, or variations of such words and phrases or state that certain actions,

events or results “may”, “could”, “would”, “might” or “will be taken”, “occur” or “be achieved”. These forward-

looking statements or information may relate to statements with respect to the activities, events or

developments that the Company expects or anticipates will or may occur in the future, including, without

limitation, the Company’s potential plans with respect to the securities of PUR . Generally, but not always,

forward-looking information and statements can be identified by the use of words such as “plans”, “expects”,

“is expected”, “budget”, “scheduled”, “estimates”, “forecasts”, “intends”, “anticipates”, or “believes” or the

negative connotation thereof or variations of such words and phrases or state that certain actions, events or

results “may”, “could”, “would”, “might” or “will be taken”, “occur” or “be achieved” or the negative

connotation thereof.

Forward-looking statements are necessarily based upon a number of assumptions that, while considered

reasonable by management at the time, are inherently subject to business, market and economic risks,

uncertainties and contingencies that may cause actual results, performance or achievements to be materially

different from those expressed or implied by forward- looking statements. Such assumptions include, but are

not limited to, assumptions that the results of planned exploration activities are as anticipated; the anticipated

mineralization of IsoEnergy’s projects being consistent with expectations and the potential benefits from such

projects and any upside from such projects; the price of uranium; that general business and economic

conditions will not change in a materially adverse manner; that financing will be available if and when needed

and on reasonable terms; that third party contractors, equipment and supplies and governmental and other

approvals required to conduct the Company’s planned activities will be available on reasonable terms and in

a timely manner. Although IsoEnergy has attempted to identify important factors that could cause actual

results to differ materially from those contained in forward- looking information, there may be other factors

that cause results not to be as anticipated, estimated or intended. There can be no assurance that such

information will prove to be accurate, as actual results and future events could differ materially from those

anticipated in such statements. Accordingl y, readers should not place undue reliance on forward- looking

information.

Such statements represent the current views of IsoEnergy with respect to future events and are necessarily

based upon a number of assumptions and estimates that, while considered reasonable by IsoEnergy, are

inherently subject to significant business, economic, competitive, political and social risks, contingencies and

uncertainties. Risks and uncertainties include, but are not limited to the following: negative operating cash

flow and dependence on third party financing; uncertainty of additional financing; no known mineral reserves;

aboriginal title and consultation issues; reliance on key management and other personnel; actual results of

exploration activities being different than anticipated; changes in exploration programs based upon results;

availability of third party contractors; availability of equipment and supplies; failure of equipment to operate

as anticipated; accidents, effects of weather and other natural phenomena; other environmental risks;

changes in laws and regulations; regulatory determinations and delays; stock market conditions generally;

demand, supply and pricing for uranium; other risks associated with the mineral exploration industry, and

general economic and political conditions in Canada, the United States and other jurisdictions where the

Company conducts business. Other factors which could materially affect such forward-looking information are

described in the risk factors in IsoEnergy’s most recent annual management’s discussion and analysis and

annual information form and IsoEnergy’s other filings with the securities regulators which are available under

the Company’s profile on SEDAR+ at www.sedarplus.ca and and on EDGAR at www.sec.gov . IsoEnergy does

not undertake to update any forward- looking information, except in accordance with applicable securities

laws.